Evidence map›Paper›PMID 35767103›Full record

ReviewAnnals of surgical oncology2022

Management of Locally Recurrent Retroperitoneal Sarcoma in the Adult: An Updated Consensus Approach from the Transatlantic Australasian Retroperitoneal Sarcoma Working Group.

William W Tseng, Carol J Swallow, Dirk C Strauss, Sylvie Bonvalot, Piotr Rutkowski, Samuel J Ford, Ricardo J Gonzalez, Rebecca A Gladdy, David E Gyorki, Mark Fairweather and 36 more

Abstract readConsensus StatementReview
PubMed Publisher
In one paragraph

Review in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  4. [European journal of nuclear medicine and molecular imaging · 2026
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  14. Bibliometric analysis of liposarcomas treatment from 2004 to 2023.Journal of cancer research and clinical oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors at 20 institutions in 10 countries.

William W TsengDivision of Surgical Oncology, Department of Surgery, City of Hope National Medical Center, Duarte, CA, USA. tsengwill@yahoo.com.
Carol J SwallowDepartment of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, and Department of Surgery, University of Toronto, Toronto, Canada. carol.swallow@sinaihealth.ca.
Dirk C StraussSarcoma Unit, Department of Surgery, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, London, UK.
Sylvie BonvalotDepartment of Surgical Oncology, Institut Curie, PSL University, Paris, France.
Piotr RutkowskiDepartment of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Samuel J FordSarcoma Unit, Queen Elizabeth Hospital, Birmingham, UK.
Ricardo J GonzalezSarcoma Department, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Rebecca A GladdyDepartment of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, and Department of Surgery, University of Toronto, Toronto, Canada.
David E GyorkiDivision of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Mark FairweatherDepartment of Surgery, Brigham and Women's Hospital, Dana Farber Cancer Institute, Boston, MA, USA.
Kyo Won LeeDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Markus AlbertsmeierDepartment of General, Visceral and Transplantation Surgery, Ludwig-Maximilians-Universität Munich, University Hospital, Munich, Germany.
Winan J van HoudtDepartment of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Magalie Fau, Bourdeaux, France.
Carolyn NessimDepartment of Surgery, The Ottawa Hospital, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Giovanni GrignaniDivision of Medical Oncology, Candiolo Cancer Institute, FPO-IRCCS, Torino, Italy.
Kenneth CardonaDivision of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Vittorio QuagliuoloSarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.
Valerie GrignolDivision of Surgical Oncology, Department of Surgery, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Jeffrey M FarmaDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.
Elisabetta PennacchioliDivision of Melanoma, Sarcoma and Rare Tumor Surgery, European Institute of Oncology, Milan, Italy.
Marco FioreDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Andrew HayesSarcoma Unit, Department of Surgery, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, London, UK.
Dimitri TzanisDepartment of Surgical Oncology, Institut Curie, PSL University, Paris, France.
Jacek SkoczylasDepartment of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Max L AlmondSarcoma Unit, Queen Elizabeth Hospital, Birmingham, UK.
John E MullinaxSarcoma Department, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Wendy JohnstonDepartment of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, and Department of Surgery, University of Toronto, Toronto, Canada.
Hayden SnowDivision of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Rick L HaasDepartment of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Dario CallegaroDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Myles J SmithSarcoma Unit, Department of Surgery, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, London, UK.
Toufik BouhadibaDepartment of Surgical Oncology, Institut Curie, PSL University, Paris, France.
Anant DesaiSarcoma Unit, Queen Elizabeth Hospital, Birmingham, UK.
Rachel VossSarcoma Department, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Roberta SanfilippoDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Robin L JonesThe Institute of Cancer Research, Chester Beatty Laboratories, London, UK.
Elizabeth H BaldiniDepartment of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, MA, USA.
Andrew J WagnerDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Charles N CattonDepartment of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Silvia StacchiottiDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Khin ThwaySarcoma Unit, Department of Pathology, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, London, UK.
Christina L RolandDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Chandrajit P RautDepartment of Surgery, Brigham and Women's Hospital, Dana Farber Cancer Institute, Boston, MA, USA.
Alessandro GronchiDepartment of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. alessandro.gronchi@istitutotumori.mi.it.
Transatlantic Australasian Retroperitoneal Sarcoma Working Group
Fondazione IRCCS Istituto Nazionale dei Tumori · ITMoffitt Cancer Center · USPrincess Margaret Cancer Centre · CAQueen Elizabeth Hospital Birmingham · GBRoyal Marsden NHS Foundation Trust · GBDana-Farber Brigham Cancer Center · USInstitut Curie · FRPeter MacCallum Cancer Centre · AUThe Maria Sklodowska-Curie National Research Institute of Oncology · PLBrigham and Women's Hospital · USCandiolo Cancer Institute · ITCity Of Hope National Medical Center · USDana-Farber Cancer Institute · USEmory University · USEuropean Institute of Oncology · ITFox Chase Cancer Center · USInstitute of Cancer Research · GBIRCCS Humanitas Research Hospital · ITLeiden University Medical Center · NLLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgery is the mainstay of treatment for retroperitoneal sarcoma (RPS), but local recurrence is common. Biologic behavior and recurrence patterns differ significantly among histologic types of RPS, with implications for management. The Transatlantic Australasian RPS Working Group (TARPSWG) published a consensus approach to primary RPS, and to complement this, one for recurrent RPS in 2016. Since then, additional studies have been published, and collaborative discussion is ongoing to address the clinical challenges of local recurrence in RPS.

methodsAn extensive literature search was performed, and the previous consensus statements for recurrent RPS were updated after review by TARPSWG members. The search included the most common RPS histologic types: liposarcoma, leiomyosarcoma, solitary fibrous tumor, undifferentiated pleomorphic sarcoma, and malignant peripheral nerve sheath tumor.

resultsRecurrent RPS management was evaluated from diagnosis to follow-up evaluation. For appropriately selected patients, resection is safe. Nomograms currently are available to help predict outcome after resection. These and other new findings have been combined with expert recommendations to provide 36 statements, each of which is attributed a level of evidence and grade of recommendation. In this updated document, more emphasis is placed on histologic type and clarification of the intent for surgical treatment, either curative or palliative. Overall, the fundamental tenet of optimal care for patients with recurrent RPS remains individualized treatment after multidisciplinary discussion by an experienced team with expertise in RPS.

conclusionsUpdated consensus recommendations are provided to help guide decision-making for treatment of locally recurrent RPS and better selection of patients who would potentially benefit from surgery.

Indexed as

Biological ProductsLiposarcomaRetroperitoneal NeoplasmsSarcomaSoft Tissue NeoplasmsAdultHumansNeoplasm Recurrence, LocalRetrospective StudiesBiological Products

Identifiers

PMID35767103
OpenAlexW4283729463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.