Evidence map›Paper›PMID 35766678›Full record

ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2022

Brazilian Thoracic Society recommendations for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension.

Caio Julio Cesar Dos Santos Fernandes, Jaquelina Sonoe Ota-Arakaki, Frederico Thadeu Assis Figueiredo Campos, Ricardo de Amorim Correa, Marcelo Basso Gazzana, Carlos Vianna Poyares Jardim, Fábio Biscegli Jatene, Jose Leonidas Alves Junior, Roberta Pulcheri Ramos, Daniela Tannus and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Multimodal treatment of chronic thromboembolic pulmonary hypertension: initial experience at a university hospital in southern Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  4. Upfront combination therapy with sildenafil and ambrisentan in patients with chronic thromboembolic pulmonary hypertension.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  5. Balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: short- and long-term results from a cohort in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Observational
  6. Article
  7. Update on the Treatment of Pulmonary Arterial Hypertension.Arquivos brasileiros de cardiologia · 2021
    Review
  8. World Pulmonary Hypertension Day: reflections and planning.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Caio Julio Cesar Dos Santos Fernandes. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-4912-021X
Jaquelina Sonoe Ota-Arakaki. Disciplina de Pneumologia. Hospital São Paulo, Escola Paulista de Medicina. Universidade Federal de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-5350-7679
Frederico Thadeu Assis Figueiredo Campos. Serviço de Pneumologia e Cirurgia Torácica, Hospital Júlia Kubistchek, Belo Horizonte (MG) Brasil.ORCID 0000-0001-6351-2343
Ricardo de Amorim Correa. Serviço de Pneumologia e Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte (MG) Brasil.ORCID 0000-0003-1779-0443
Marcelo Basso Gazzana. Serviço de Pneumologia, Hospital de Clínicas de Porto Alegre, Porto Alegre (RS) Brasil.ORCID 0000-0003-0086-1890
Carlos Vianna Poyares Jardim. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0003-0425-5548
Fábio Biscegli Jatene. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0001-6175-5595
Jose Leonidas Alves Junior. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0001-8943-1947
Roberta Pulcheri Ramos. Disciplina de Pneumologia. Hospital São Paulo, Escola Paulista de Medicina. Universidade Federal de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-2383-6527
Daniela Tannus. Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia (GO) Brasil.ORCID 0000-0003-1305-7914
Carlos Teles. Disciplina de Pneumologia. Hospital São Paulo, Escola Paulista de Medicina. Universidade Federal de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-8945-8813
Mario Terra Filho. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0002-8642-5354
Daniel Waetge. Disciplina de Pneumologia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil.ORCID 0000-0002-5265-1126
Rogerio Souza. Grupo de Circulação Pulmonar, Divisão de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID 0000-0003-2789-9143
Universidade de São Paulo · BRCompanhia Energética de São Paulo · BRHospital São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital de Clínicas de Porto Alegre · BRUniversidade Federal de Goiás · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious and debilitating disease caused by occlusion of the pulmonary arterial bed by hematic emboli and by the resulting fibrous material. Such occlusion increases vascular resistance and, consequently, the pressure in the region of the pulmonary artery, which is the definition of pulmonary hypertension. The increased load imposed on the right ventricle leads to its progressive dysfunction and, finally, to death. However, CTEPH has a highly significant feature that distinguishes it from other forms of pulmonary hypertension: the fact that it can be cured through treatment with pulmonary thromboendarterectomy. Therefore, the primary objective of the management of CTEPH should be the assessment of patient fitness for surgery at a referral center, given that not all patients are good candidates. For the patients who are not good candidates for pulmonary thromboendarterectomy, the viable therapeutic alternatives include pulmonary artery angioplasty and pharmacological treatment. In these recommendations, the pathophysiological bases for the onset of CTEPH, such as acute pulmonary embolism and the clinical condition of the patient, will be discussed, as will the diagnostic algorithm to be followed and the therapeutic alternatives currently available.

Indexed as

Hypertension, PulmonaryPulmonary EmbolismBrazilChronic DiseaseEndarterectomyHumansPulmonary Artery

Identifiers

PMID35766678
PMCPMC9233986
OpenAlexW3042926411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.