Evidence map›Paper›PMID 35766669›Full record

ArticleActa cirurgica brasileira2022

Effect of electrophysical resources on healing of neurotendinous injury in an experimental model of type I diabetes and kidney disease.

Patrícia Henrique Silva, Pâmela Henrique Silva, Gilberto Gonçalves Facco, Adalberto Vieira Corazza, Josivaldo Godoy da Silva, Iandara Schettert Silva

Abstract read
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Article in Acta cirurgica brasileira, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Patrícia Henrique SilvaFellow Master's degree. Universidade Federal do Mato Grosso do Sul - Postgraduate Program in Health and Development - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0002-6905-5646
Pâmela Henrique SilvaFellow Master's degree. Universidade Federal do Mato Grosso do Sul - Postgraduate Program in Health and Development - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0003-1133-7752
Gilberto Gonçalves FaccoPhD. Universidade Anhanguera - Postgraduate Program in Environments and Regional Development - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0002-6434-2398
Adalberto Vieira CorazzaPhD. Universidade Federal do Mato Grosso do Sul - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0003-4888-1380
Josivaldo Godoy da SilvaPhD. Universidade Federal do Mato Grosso do Sul - Postgraduate Program in Health and Development - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0003-0663-2087
Iandara Schettert SilvaPhD. Universidade Federal do Mato Grosso do Sul - Postgraduate Program in Health and Development - Campo Grande (MS), Brazil.ORCID http://orcid.org/0000-0001-9431-098X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate and describe the effect of electrophysical resources laser therapy (LLLT), intravascular laser blood irradiation (ILIB), and cryotherapy on the healing process of neurotendinous injury, as well as possible systemic changes, in the experimental model of type 1 diabetes associated with kidney injury.

methodsThe animals were randomized into four groups: G1) healthy control with untreated injury; G2) healthy control with injury and treatment; G3) disease control with untreated lesion; G4) disease with injury and treatment. Furthermore, the treated groups were divided into three, according to the type of treatment. All animals were induced to neurotendinous injury and treated according to the therapeutic protocols. Healing and inflammation were analyzed by semiquantitative histopathological study.

resultsIt was observed in sick animals treated with cryotherapy and ILIB reduction of inflammatory exudate, presence of fibroblasts and organization of collagen, when compared to the effects of LLLT. Moreover, there was reduction in glycemic levels in the group treated with ILIB.

conclusionsCryotherapy promoted reduction in inflammatory exudate and organization of collagen fibers, in addition to the absence of signs of tissue necrosis, in the groups treated with and without the disease. ILIB therapy showed the same findings associated with significant reduction in glycemic levels in the group of diseased animals. The application of LLLT showed increased inflammatory exudate, low organization of collagen fibers and low sign of tissue degeneration and necrosis. This study in a model of associated diseases (diabetes and kidney disease) whose effects of electrophysical resources studied after neurotendinous injury allows us to verify histopathological variables suggestive of patients with the same comorbidities.

Indexed as

Diabetes Mellitus, Type 1Kidney DiseasesLow-Level Light TherapyAnimalsCollagenModels, TheoreticalNecrosisCollagen

Identifiers

PMID35766669
PMCPMC9239559

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