Evidence map›Paper›PMID 35766531›Full record

ReviewAJR. American journal of roentgenology2022

Radiomics in Abdominopelvic Solid-Organ Oncologic Imaging: Current Status.

Xiaoyang Liu, Mohamed G Elbanan, Antonio Luna, Masoom A Haider, Andrew D Smith, Carl F Sabottke, Bradley M Spieler, Baris Turkbey, David Fuentes, Ahmed Moawad and 3 more

Abstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Radiomics and radiogenomics in ovarian cancer: a review with a focus on ultrasound applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaoyang LiuJoint Department of Medical Imaging, Division of Abdominal Imaging, University Health Network, University of Toronto, ON, Canada.
Mohamed G ElbananDepartment of Radiology, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT.
Antonio LunaDepartment of Imaging, HT Médica, Jaén, Spain.
Masoom A HaiderLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Andrew D SmithDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Carl F SabottkeDepartment of Medical Imaging, University of Arizona College of Medicine, Tucson, AZ.
Bradley M SpielerDepartment of Radiology, University Medical Center, Louisiana State University Health Sciences Center, New Orleans, LA.
Baris TurkbeyMolecular Imaging Program, National Cancer Institute, NIH, Bethesda, MD.
David FuentesDepartment of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX.
Ahmed MoawadDepartment of Diagnostic and Interventional Radiology, Mercy Catholic Medical Center, Darby, PA.
Serageldin KamelDepartment of Lymphoma, University of Texas MD Anderson Cancer Center, Houston, TX.
Natally HorvatDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Khaled M ElsayesDepartment of Abdominal Imaging, University of Texas MD Anderson Cancer Center, 1400 Pressler St, Houston, TX 77030.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Imaging, image guided biopsy and treatment of prostate cancerZIABC012062 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TÜRKBEY, BARIS · 2021 to 2025
$1.3M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Radiomics is the process of extraction of high-throughput quantitative imaging features from medical images. These features represent noninvasive quantitative biomarkers that go beyond the traditional imaging features visible to the human eye. This article first reviews the steps of the radiomics pipeline, including image acquisition, ROI selection and image segmentation, image preprocessing, feature extraction, feature selection, and model development and application. Current evidence for the application of radiomics in abdominopelvic solid-organ cancers is then reviewed. Applications including diagnosis, subtype determination, treatment response assessment, and outcome prediction are explored within the context of hepatobiliary and pancreatic cancer, renal cell carcinoma, prostate cancer, gynecologic cancer, and adrenal masses. This literature review focuses on the strongest available evidence, including systematic reviews, meta-analyses, and large multicenter studies. Limitations of the available literature are highlighted, including marked heterogeneity in radiomics methodology, frequent use of small sample sizes with high risk of overfitting, and lack of prospective design, external validation, and standardized radiomics workflow. Thus, although studies have laid a foundation that supports continued investigation into radiomics models, stronger evidence is needed before clinical adoption.

Indexed as

Medical OncologyNeoplasmsFemaleHumansMalePrognosisWorkflowabdomenfeaturesoncologyradiomicstexture

Identifiers

PMID35766531
PMCPMC10616929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.