Evidence map›Paper›PMID 35766508›Full record

ArticleAntimicrobial agents and chemotherapy2022

MBZM-N-IBT, a Novel Small Molecule, Restricts Chikungunya Virus Infection by Targeting nsP2 Protease Activity

Saikat De, Soumyajit Ghosh, Supriya Suman Keshry, Chandan Mahish, Chinmayee Mohapatra, Ankeeta Guru, Prabhudutta Mamidi, Ankita Datey, Sweta Smita Pani, Dileep Vasudevan and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  8. Network Pharmacology, Molecular Docking andCurrent computer-aided drug design · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Saikat DeInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.ORCID 0000-0003-2028-0428
Soumyajit Ghosh *Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Supriya Suman Keshry *Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Chandan MahishNational Institute of Science Education and Research, Bhubaneswar, Odisha, India.
Chinmayee MohapatraInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Ankeeta GuruInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Prabhudutta MamidiInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Ankita DateyInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Sweta Smita PaniInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Dileep VasudevanInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Tushar Kant BeuriaInstitute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.
Subhasis ChattopadhyayNational Institute of Science Education and Research, Bhubaneswar, Odisha, India.
Bharat Bhusan Subudhi *School of Pharmaceutical Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha, India.
Soma Chattopadhyay *Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.ORCID 0000-0001-8378-1014
Institute of Life Sciences · INNational Institute of Science Education and Research · INRegional Centre for Biotechnology · INSiksha O Anusandhan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in disease incidences and persistent Chikungunya virus (CHIKV)-induced arthritis have been a huge burden on public health globally. In the absence of specific antivirals or vaccines, it is essential to continue efforts to develop effective anti-CHIKV strategies. Our previous study showing the

Indexed as

Chikungunya FeverChikungunya virusAnimalsBenzimidazolesHumansIsatinLeukocytes, MononuclearMiceMice, Inbred C57BLPeptide HydrolasesVirus Replication1-((2-methylbenzimidazol-1-yl)methyl)-2-oxoindolin-3-ylidene)amino)thioureaBenzimidazolesIsatinPeptide Hydrolasesanti-viralChikungunyainfectioninflammationreplication

Identifiers

PMID35766508
PMCPMC9295557
OpenAlexW4283719907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.