Evidence map›Paper›PMID 35766481›Full record

ArticleEuropean journal of translational myology2022

The role of bone mineral density and cartilage volume to predict knee cartilage degeneration.

Federica Kiyomi Ciliberti, Giuseppe Cesarelli, Lorena Guerrini, Arnar Evgeni Gunnarsson, Riccardo Forni, Romain Aubonnet, Marco Recenti, Deborah Jacob, Halldór Jónsson, Vincenzo Cangiano and 3 more

Open access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Federica Kiyomi CilibertiInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. federica21@ru.is.
Giuseppe CesarelliDepartment of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Naples. giuseppe.cesarelli@unina.it.
Lorena GuerriniInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. lorenag@ru.is.
Arnar Evgeni GunnarssonInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. arnareg@ru.is.
Riccardo ForniInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik, Iceland; Department of Electrical, Electronic and Information Engineering "Guglielmo Marconi" (DEI), University of Bologna, Cesena. riccardo21@ru.is.
Romain AubonnetInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. romaina@ru.is.
Marco RecentiInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. marco18@ru.is.
Deborah JacobInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. deborah20@ru.is.
Halldór JónssonDepartment of Orthopaedics, Landspitali, University Hospital of Iceland, Reykjavik, Iceland; Medical Faculty, University of Iceland, Reykjavik. halldor@landspitali.is.
Vincenzo CangianoInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik. vincenzocangiano74@gmail.com.
Anna Sigríður IslindDepartment of Computer Science, Reykjavik University, Reykjavik. annasi@ru.is.
Monica GambacortaUmberto I Hospital, Local Health Unit of Salerno, Salerno. m.gambacorta@aslsalerno.it.
Paolo GargiuloInstitute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik, Iceland; Department of Science, Landspitali, University Hospital of Iceland, Reykjavik. paolo@ru.is.
Reykjavík University · ISUniversity of Naples Federico II · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knee Osteoarthritis (OA) is a highly prevalent condition affecting knee joint that causes loss of physical function and pain. Clinical treatments are mainly focused on pain relief and limitation of disabilities; therefore, it is crucial to find new paradigms assessing cartilage conditions for detecting and monitoring the progression of OA. The goal of this paper is to highlight the predictive power of several features, such as cartilage density, volume and surface. These features were extracted from the 3D reconstruction of knee joint of forty-seven different patients, subdivided into two categories: degenerative and non-degenerative. The most influent parameters for the degeneration of the knee cartilage were determined using two machine learning classification algorithms (logistic regression and support vector machine); later, box plots, which depicted differences between the classes by gender, were presented to analyze several of the key features' trend. This work is part of a strategy that aims to find a new solution to assess cartilage condition based on new-investigated features.

Identifiers

PMID35766481
PMCPMC9295173
OpenAlexW4283656105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.