Evidence map›Paper›PMID 35766454›Full record

ArticleMedical physics2022

Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography.

Martin Lyngby Lassen, Evangelos Tzolos, Tinsu Pan, Jacek Kwiecinski, Sebastien Cadet, Damini Dey, Daniel Berman, Piotr Slomka

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Fully Automated, Fast Motion Correction of Dynamic Whole-Body and Total-Body PET/CT Imaging Studies.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  3. Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.Journal of cardiovascular development and disease · 2023
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Martin Lyngby LassenDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Evangelos TzolosDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Tinsu PanDepartment of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Jacek KwiecinskiDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sebastien CadetDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Damini DeyDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Daniel BermanDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Piotr SlomkaDepartment of Medicine (Division of Artificial Intelligence), Biomedical Sciences, and Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Cedars-Sinai Medical Center · USInstitute of Cardiology · PLThe University of Texas MD Anderson Cancer Center · US

Funding

Integrated analysis of coronary anatomy and biology with 18F-fluoride PET and CT angiographyR01HL135557 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2017 to 2020
$3.0M
National Heart, Lung, and Blood Institute/National Institute of Health (NHLBI/NIH)NHLBI NIH HHS R01 HL135557
6 · The paper itself

Abstract

backgroundRespiratory motion correction is of importance in studies of coronary plaques employing PURPOSE: To investigate the accuracy of the motion correction employed in a software (FusionQuant) used for evaluation of

methodsThis study included 23 patients who undertook thoracic PET scans for the assessment of coronary plaques using

resultsIn total, 19 coronary plaques were identified in 16 patients. No statistical differences were observed for the maximum respiratory motion observed in x, y, and the 3D motion fields (magnitude and direction) between the CT and PET (X direction: 4D CT = 2.5 ± 1.5 mm, PET = 2.4 ± 3.2 mm; Y direction: 4D CT = 2.3 ± 1.9 mm, PET = 0.7 ± 2.9 mm, 3D motion: 4D CT = 6.6 ± 3.1 mm, PET = 5.7 ± 2.6 mm, all p ≥ 0.05). Significant differences in respiratory motion were observed in the systems' Z direction: 4D CT = 4.9 ± 3.4 mm, PET = 2.3 ± 3.2 mm, p = 0.04. Significantly improved SNR is reported for the motion corrected images compared to the end-expiratory phase images (end-expiratory phase = 6.8±4.8, motion corrected = 12.2±4.5, p = 0.001).

conclusionSimilar respiratory motion was observed in two directions and 3D for coronary plaques on 4D CT as detected by automatic respiratory motion correction of coronary PET using FusionQuant. The respiratory motion correction technique significantly improved the SNR in the images.

Indexed as

Four-Dimensional Computed TomographySodium FluorideHumansPositron-Emission TomographySodiumSodiumSodium Fluoride18F-sodium fluoridemotion correctionPET/CT

Identifiers

PMID35766454
PMCPMC9742185
OpenAlexW4283732342

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.