Evidence map›Paper›PMID 35766280›Full record

Observational studyJournal of the American Heart Association2022

Bidirectional Longitudinal Relationships Between Arterial Stiffness and Hypertension Are Independent of Those Between Arterial Stiffness and Diabetes: A Large-Scale Prospective Observational Study in Employees of a Japanese Company.

Hiroki Nakano, Kazuki Shiina, Takamichi Takahashi, Masatsune Fujii, Yoichi Iwasaki, Chisa Matsumoto, Akira Yamashina, Taishiro Chikamori, Hirofumi Tomiyama

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. SerumLife (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Vascular function: a key player in hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hiroki NakanoDepartment of Cardiology Tokyo Medical University Tokyo Japan.ORCID 0000-0003-1487-3702
Kazuki ShiinaDepartment of Cardiology Tokyo Medical University Tokyo Japan.ORCID 0000-0002-7293-2064
Takamichi TakahashiDepartment of Cardiology Tokyo Medical University Tokyo Japan.
Masatsune FujiiDepartment of Cardiology Tokyo Medical University Tokyo Japan.
Yoichi IwasakiDepartment of Cardiology Tokyo Medical University Tokyo Japan.
Chisa MatsumotoDepartment of Cardiology Tokyo Medical University Tokyo Japan.ORCID 0000-0002-8066-8363
Akira YamashinaDepartment of Nursing Kiryu University Gunma Japan.
Taishiro ChikamoriDepartment of Cardiology Tokyo Medical University Tokyo Japan.
Hirofumi TomiyamaDepartment of Cardiology Tokyo Medical University Tokyo Japan.ORCID 0000-0002-8373-7862
Tokyo Medical University · JPKiryu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hypertension and diabetes frequently coexist; however, it has not yet been clarified if the bidirectional longitudinal relationships between arterial stiffness and hypertension are independent of those between arterial stiffness and diabetes. Methods and Results In this 16-year prospective observational study, 3960 middle-aged employees of a Japanese company without hypertension/diabetes at the study baseline underwent annual repeated measurements of blood pressure, serum glycosylated hemoglobin A

Indexed as

Diabetes MellitusHypertensionPrediabetic StatePrehypertensionVascular StiffnessAnkle Brachial IndexHumansJapanMiddle AgedPulse Wave AnalysisRisk Factorsarterial stiffnessdiabeteshypertension

Identifiers

PMID35766280
PMCPMC9333383
OpenAlexW4283729915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.