Evidence map›Paper›PMID 35766144›Full record

ArticleCancer medicine2023

Artificial intelligence assisted cytological detection for early esophageal squamous epithelial lesions by using low-grade squamous intraepithelial lesion as diagnostic threshold.

Bin Yao, Yadong Feng, Kai Zhao, Yan Liang, Peilin Huang, Juncai Zang, Jie Song, Mengjie Li, Xiaofen Wang, Huazhong Shu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Bin YaoThe Laboratory of Image Science and Technology, Southeast University, Nanjing, China.
Yadong FengDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.ORCID 0000-0001-9259-3840
Kai ZhaoDepartment of Gastroenterology, Jintan First People's Hospital Affiliated to Jiangsu University, Changzhou, China.
Yan LiangDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Peilin HuangSchool of Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Juncai ZangFroeasy Technology Development CO., LTD, Red Maple Park of Technological Industry, Nanjing, China.
Jie SongDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Mengjie LiDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Xiaofen WangDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.
Huazhong ShuThe Laboratory of Image Science and Technology, Southeast University, Nanjing, China.
Ruihua ShiDepartment of Gastroenterology, School of Medicine, Zhongda Hospital Southeast University, Nanjing, China.ORCID 0000-0003-4977-8801
Zhongda Hospital Southeast University · CNJiangsu University · CNNanjing University of Industry Technology · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManual cytological diagnosis for early esophageal squamous cell carcinoma (early ESCC) and high-grade intraepithelial neoplasia (HGIN) is unsatisfactory. Herein, we have introduced an artificial intelligence (AI)-assisted cytological diagnosis for such lesions.

methodsLow-grade squamous intraepithelial lesion or worse was set as the diagnostic threshold for AI-assisted diagnosis. The performance of AI-assisted diagnosis was evaluated and compared to that of manual diagnosis. Feasibility in large-scale screening was also assessed.

resultsAI-assisted diagnosis for abnormal cells was superior to manual reading by presenting a higher efficiency for each slide (50.9 ± 0.8 s vs 236.8 ± 3.9 s, p = 1.52 × 10

conclusionOur study provides a novel cytological method for detecting and screening early ESCC and HGIN.

Indexed as

Carcinoma in SituEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaSquamous Intraepithelial LesionsUterine Cervical NeoplasmsArtificial IntelligenceFemaleHumansAI-assisted diagnosiscytologyearly esophageal squamous cell cancerprecursor lesionscreening

Identifiers

PMID35766144
PMCPMC9883535
OpenAlexW4283722030

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.