ArticleTransboundary and emerging diseases2022
The enteric virome of cats with feline panleukopenia differs in abundance and diversity from healthy cats.
Article in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 25 citations in OpenAlex.
- Gut Microbiome Disruption in Shelter Cats with Feline Panleukopenia: Virome Co-Detection and Enteric Dysbiosis.Biology · 2026Review
- Localized adaptive evolution in VP1 drives antigenic divergence of feline calicivirus despite high sequence conservation.Veterinary research · 2026Article
- Low prevalence and frequent co-detection of feline astrovirus with feline enteric coronavirus and feline bocaparvovirus in asymptomatic cats in Japan.Archives of virology · 2026Article
- The Multiplex qPCR Assay Enables Simultaneous Detection, Differentiation, and Quantification of Feline Bocavirus-1, -2, and -3 in Clinical Samples.Transboundary and emerging diseases · 2026Article
- Genetic variability and phylogenetic analysis of the VP2 gene of feline parvovirus in Harbin.Frontiers in veterinary science · 2026Article
- Prospective investigation of feline bocavirus persistence and shedding in naturally infected cats from varied household settings.Journal of feline medicine and surgery · 2025Article
- Genetic and Statistical Study of Anelloviruses and Gyroviruses in Diarrheic Cats and Their Co-Occurrence Patterns.Viruses · 2025Article
- Taxonomic and functional profiling of bat guano microbiota from hiking trail-associated tunnels: a potential risk for human health?Environmental microbiome · 2025Article
- Detection of felipivirus in feces samples from cats in an animal shelter in Japan.The Journal of veterinary medical science · 2025Article
- Identification and Pathogenicity Analysis of Feline Calicivirus in Shanghai and Guangdong, China.Transboundary and emerging diseases · 2025Article
- Genetic analysis of feline parvovirus reveals predominance of feline parvovirus-G1 group among cats in China.The Journal of veterinary medical science · 2024Article
- Demographic and zoological drivers of infectome diversity in companion cats with ascites.mSystems · 2024Article
- Metagenomic analysis reveals high diversity of gut viromes in yaks (Bos grunniens) from the Qinghai-Tibet Plateau.Communications biology · 2024Article
- Article
- Viral metagenomic analysis reveals diverse viruses and a novel bocaparvovirus in the enteric virome of snow leopard (Heliyon · 2024Article
- Prevalence and Molecular Evolution of Parvovirus in Cats in Eastern Shandong, China, between 2021 and 2022.Transboundary and emerging diseases · 2024Article
- Two novel sites determine genetic relationships between CPV-2 and FPV: an epidemiological survey of canine and feline parvoviruses in Changchun, China (2020).Frontiers in veterinary science · 2024Article
- Exploring the Enteric Virome of Cats with Acute Gastroenteritis.Veterinary sciences · 2023Article
- Molecular identification ofFrontiers in veterinary science · 2023Article
- The enteric virome of cats with feline panleukopenia differs in abundance and diversity from healthy cats.Transboundary and emerging diseases · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feline panleukopenia (FPL) is a severe, often fatal disease caused by feline panleukopenia virus (FPV). How infection with FPV might impact the composition of the entire eukaryotic enteric virome in cats has not been characterized. We used meta-transcriptomic and viral particle enrichment metagenomic approaches to characterize the enteric viromes of 23 cats naturally infected with FPV (FPV-cases) and 36 age-matched healthy shelter cats (healthy controls). Sequencing reads from mammalian infecting viral families largely belonged to the Coronaviridae, Parvoviridae and Astroviridae. The most abundant viruses among the healthy control cats were feline coronavirus, Mamastrovirus 2 and Carnivore bocaparvovirus 3 (feline bocavirus), with frequent coinfections of all three. Feline chaphamaparvovirus was only detected in healthy controls (6 out of 36, 16.7%). Among the FPV-cases, in addition to FPV, the most abundant viruses were Mamastrovirus 2, feline coronavirus and C. bocaparvovirus 4 (feline bocaparvovirus 2). The latter and feline bocaparvovirus 3 were detected significantly more frequently in FPV-cases than in healthy controls. Feline calicivirus was present in a higher proportion of FPV-cases (11 out of 23, 47.8%) compared to healthy controls (5 out of 36, 13.9%, p = 0.0067). Feline kobuvirus infections were also common among FPV-cases (9 out of 23, 39.1%) and were not detected in any healthy controls (p < .0001). While abundant in both groups, astroviruses were more frequently present in FPV-cases (19 out of 23, 82.6%) than in healthy controls (18 out of 36, p = .0142). The differences in eukaryotic virome composition revealed here indicate that further investigations are warranted to determine associations between enteric viral co-infections on clinical disease severity in cats with FPL.
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