ArticleInternational journal of methods in psychiatric research2022
Cardiovascular risk factors in attention-deficit/hyperactivity disorder: A family design study of Swedish conscripts.
Article in International journal of methods in psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Trends in Body Mass Index Among Individuals With Neurodevelopmental Disorders.JAMA network open · 2024Article
- Changes in parental attitudes toward attention-deficit/hyperactivity disorder impairment over time.JCPP advances · 2024Article
- Methylphenidate and Short-Term Cardiovascular Risk.JAMA network open · 2024Article
- Exploring Differences in Physical Health in Young Children With and Without ADHD.Journal of pediatric psychology · 2024Article
- Psychiatric comorbidities in women with cardiometabolic conditions with and without ADHD: a population-based study.BMC medicine · 2023Article
- Childhood attention-deficit hyperactivity disorder problems and mid-life cardiovascular risk: prospective population cohort study.The British journal of psychiatry : the journal of mental science · 2023Article
- Predicting childhood and adolescent attention-deficit/hyperactivity disorder onset: a nationwide deep learning approach.Molecular psychiatry · 2023Article
- Cardiovascular risk factors in attention-deficit/hyperactivity disorder: A family design study of Swedish conscripts.International journal of methods in psychiatric research · 2022Article
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Authors and funding
8 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective(1) investigate the associations of attention-deficit/hyperactivity disorder (ADHD) with systolic and diastolic blood pressure, resting heart rate, pulse pressure (PP), physical fitness, and BMI; (2) explore whether cardiovascular risk factors and ADHD share genetic and environmental influences; (3) assess if pharmacological treatment for ADHD influences these associations.
methodsWe identified 395,978 individuals born between 1973 and 1991 who had military conscription examinations at a mean age of 18.3 years (SD = 0.57) and their full-siblings within the same cohort (N = 208,060) by linking population-based registers in Sweden.
resultsSignificantly increased risk of ADHD was observed in individuals with low systolic blood pressure (SBP) and PP, low physical fitness, and in those who had overweight or obesity after adjustments (adjusted Odds Ratio [OR] ranging from 1.10 to 1.45). Full siblings of individuals with low SBP, low physical fitness, and obesity were more likely to receive an ADHD diagnosis compared to full siblings without those risk factors (OR ranging from 1.17 to 1.31). Additionally, analyses showed robust associations between ADHD and low SBP, low physical fitness, and obesity, even in ADHD medication-naïve individuals.
conclusionsIndividuals with several cardiovascular risk factors are more often diagnosed with ADHD, regardless of psychiatric comorbidity. These association are not explained by ADHD pharmacotherapy, rather, they are in part due to shared familial risk factors.
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