Evidence map›Paper›PMID 35765710›Full record

ArticleJournal of cellular and molecular medicine2022

Acacetin resists UVA photoaging by mediating the SIRT3/ROS/MAPKs pathway.

Jing Mu, Hong Chen, Mengyi Ye, Xiaoxia Zhang, Huisheng Ma

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

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  8. Investigating the Health Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Sirtuins as Players in the Signal Transduction ofInternational journal of molecular sciences · 2024
    Review
  15. Review
  16. Acacetin resists UVA photoaging by mediating the SIRT3/ROS/MAPKs pathway.Journal of cellular and molecular medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing MuSchool of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan, China.ORCID 0000-0002-8687-9743
Hong ChenSchool of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan, China.
Mengyi YeSchool of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan, China.
Xiaoxia ZhangSchool of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan, China.
Huisheng MaSchool of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan, China.
Ningxia Medical University · CN

Funding

National Natural Science Foundation of China 81960893
6 · The paper itself

Abstract

Ultraviolet A (UVA) radiation is a major contributor to the pathogenesis of skin photoaging, and the aim of this study was to investigate the effect of Acacetin on skin photoaging in UVA-irradiated mice and human dermal fibroblasts (HDF). Healthy dorsal depilated rats were irradiated with UVA 30 J/cm

Indexed as

Sirtuin 3Skin AgingSkin DiseasesAnimalsFibroblastsFlavonesHumansMatrix MetalloproteinasesMiceMitogen-Activated Protein KinasesRatsReactive Oxygen SpeciesSignal TransductionSkinTransforming Growth Factor betaUltraviolet RaysacacetinFlavonesMatrix MetalloproteinasesMitogen-Activated Protein KinasesReactive Oxygen SpeciesSIRT3 protein, humanSirt3 protein, mouseSirtuin 3Transforming Growth Factor betaacacetinMAPKROSSIRT3UVA irradiation

Identifiers

PMID35765710
PMCPMC9357640
OpenAlexW4283688792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.