ArticleGenome biology2022
Storing and analyzing a genome on a blockchain.
Article in Genome biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Comprehensive Review of the Revolutionary Potential of Blockchain in Safe, Secure, and Sustainable Pharmaceutical Operations.Pharmaceutical research · 2026Pooled it
- A systematic study on blockchain technology for genomic data management in healthcare: approaches, challenges, and research opportunities.Medical & biological engineering & computing · 2026Pooled it
- Toward owner governance in genomic data privacy with Governome.Cell reports methods · 2025Article
- Recent advances and future prospects for blockchain in biomedicine.Cell reports methods · 2025Review
- Scalable and efficient on-chain data management in blockchain for large biomedical data.Journal of biomedical informatics · 2025Article
- A framework for sharing of clinical and genetic data for precision medicine applications.Nature medicine · 2024Article
- Integrating population-based biobanks: Catalyst for advances in precision health.Computational and structural biotechnology journal · 2024Article
- Assessing transcriptomic reidentification risks using discriminative sequence models.Genome research · 2023Article
- GATTACA is still pertinent 25 years later.Nature genetics · 2022Article
- A scoping review of distributed ledger technology in genomics: thematic analysis and directions for future research.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Storing and analyzing a genome on a blockchain.Genome biology · 2022Article
- Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases.Frontiers in digital health · 2022Review
- Two-Level Blockchain System for Digital Crime Evidence Management.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
There are major efforts underway to make genome sequencing a routine part of clinical practice. A critical barrier to these is achieving practical solutions for data ownership and integrity. Blockchain provides solutions to these challenges in other realms, such as finance. However, its use in genomics is stymied due to the difficulty in storing large-scale data on-chain, slow transaction speeds, and limitations on querying. To overcome these roadblocks, we developed a private blockchain network to store genomic variants and reference-aligned reads on-chain. It uses nested database indexing with an accompanying tool suite to rapidly access and analyze the data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.