Evidence map›Paper›PMID 35765049›Full record

ArticleBMC oral health2022

A rare case of multiple brain abscesses caused by apical periodontitis of deciduous teeth in congenital heart disease: a case report.

Shizuka Takahashi, Hisato Segoe, Takashi Kikuiri, Yuji Maruo, Tomonobu Sato, Yutaka Watanabe, Zhao Jimei, Yoshitaka Yoshimura, Misa Ishiyama, Atsuhito Takeda and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Paediatric brain abscesses and odontogenic infection: a critical analysis of the existing literature.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Shizuka Takahashi *Department of Dentistry for Children and Disabled Person, Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Hisato Segoe *Department of Pediatrics, Japanese Red Cross Kitami Hospital, Kitami, 090-8666, Japan.
Takashi KikuiriDepartment of Pediatric Dentistry, Nihon University School of Dentistry, Tokyo, 101-8310, Japan. kikuiri.takashi@nihon-u.ac.jp.ORCID 0000-0003-2132-8702
Yuji MaruoDepartment of Pediatrics, Japanese Red Cross Kitami Hospital, Kitami, 090-8666, Japan.
Tomonobu SatoDepartment of Pediatrics, Japanese Red Cross Kitami Hospital, Kitami, 090-8666, Japan.
Yutaka WatanabeDepartment of Dentistry for Gerodontology, Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Zhao JimeiDepartment of Dentistry for Children and Disabled Person, Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Yoshitaka YoshimuraDepartment of Molecular Cell Pharmacology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Misa IshiyamaDepartment of Pediatric Dentistry, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Atsuhito TakedaDepartment of Pediatrics, Graduate School of Medicine, Hokkaido University, Sapporo, 060-8648, Japan.
Yasutaka YawakaDepartment of Dentistry for Children and Disabled Person, Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Tetsuo ShirakawaDepartment of Pediatric Dentistry, Nihon University School of Dentistry, Tokyo, 101-8310, Japan.
Hokkaido University · JPJapanese Red Cross Hokkaido College of Nursing · JPNihon University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA brain abscess is a focal infection in which abscesses form in the brain. A brain abscess is a rare but fatal disease when rupture occurs into the ventricles. We report a case of multiple brain abscesses caused by a hematogenous infection from the apical periodontitis of deciduous teeth. CASE PRESENTATION: The patient was a 7-years and 8-months-old male with congenital heart disease. The patient sought medical attention due to fever and headache, for which he was started on three antibiotics with a diagnosis of multiple brain abscesses. Given that apical periodontitis of deciduous teeth was strongly suspected as the source of the brain abscess, the deciduous teeth were extracted. Immediately after deciduous teeth extraction, the patient's headache and neurological symptoms disappeared.

conclusionsAfter teeth extraction, a clear shrinkage of the brain abscess was observed, and the patient was discharged from the hospital.

Indexed as

Brain AbscessHeart Defects, CongenitalPeriapical PeriodontitisHeadacheHumansInfantMaleTooth, DeciduousApical periodontitisCongenital heart diseaseDeciduous teeth cariesMultiple brain abscesses

Identifiers

PMID35765049
PMCPMC9241206
OpenAlexW4283662651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.