Evidence map›Paper›PMID 35764995›Full record

ArticleBMC health services research2022

Rationale and design of Children's Oncology Group (COG) study ACCL20N1CD: financial distress during treatment of acute lymphoblastic leukemia in the United States.

Melissa Beauchemin, Sheila Judge Santacroce, Kira Bona, Ha Dang, Sarah Alexander, Kamala Allen, Crystal De Los Santos, Beth Fisher, Yudy Muñeton-Castaño, Olivia Ponce and 4 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04928599 active not recruitingnot on this map

Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States

TypeobservationalSponsorChildren's Oncology GroupRan2022 to 2028Enrolled100ConditionsAcute Lymphoblastic LeukemiaArmsElectronic Health Record Review, Interview, Survey Administration
NCT06814795 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility of Medically Tailored Meals for Pediatric Populations at Risk for Disparities in Serious Illness Outcomes Due to Inequities in Social Drivers of Health (MTM-Kids)

TypeinterventionalSponsorUNC Lineberger Comprehensive Cancer CenterRan2025 to 2026Enrolled32ConditionsPediatric CancerArmsMedically tailored meals
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  6. Financial toxicity among pediatric oncology families during therapy and early survivorship: a qualitative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Melissa BeaucheminColumbia University School of Nursing, New York, NY, USA. mmp2123@cumc.columbia.edu.ORCID http://orcid.org/0000-0003-4058-1586
Sheila Judge SantacroceSchool of Nursing, University of North Carolina Chapel Hill, Chapel Hill, NC, USA.
Kira BonaDepartment of Pediatric Oncology, Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MB, USA.
Ha DangDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.
Sarah AlexanderHospital for Sick Children, Toronto, ON, USA.
Kamala AllenDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.
Crystal De Los SantosDriscoll Children's Hospital, Corpus Christi, TX, USA.
Beth FisherChildren's Healthcare of Atlanta, Atlanta, GA, USA.
Yudy Muñeton-CastañoDana-Farber Cancer Institute, Boston, MA, USA.
Olivia PonceChildren's Oncology Group, Monrovia, CA, USA.
Sarah VargasChildren's Oncology Group, Monrovia, CA, USA.
Aaron SugalskiUniversity of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Lillian SungHospital for Sick Children, Toronto, ON, USA.
Susan ParsonsTufts Medical Center, Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.

Funding

Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

backgroundThe study purpose is to describe trajectories of financial distress for parents of children (ages 1-14.9 years) with newly diagnosed acute lymphoblastic leukemia (ALL). The secondary aim is to identify multilevel factors (child, parent, household, treating institution) that influence change in financial distress over time.

methodsThe study uses a prospective cohort design, repeated measurements, and mixed methods. The settings are Children's Oncology Group (COG) institutions participating in the National Cancer Institute Community Oncology Research Program (NCORP). Eligible participants are English- and/or Spanish-speaking parents or legal guardians (hereafter "parents") of index children. Parents are asked to complete a survey during their child's induction (T1) and maintenance therapy (T2), and near treatment completion (T3). Study surveys include items about (a) the child's cancer and clinical course, (b) parental socio-economic status, financial distress and financial coping behaviors, and (c) household material hardships. At least 15 parents will be invited to participate in an optional semi-structured interview. NCORP institutions that enroll at least one parent must complete an annual survey about institution resources that could influence parental financial distress. DISCUSSION: The results will inform future interventions to mitigate financial distress for parents of children diagnosed with ALL and could be instructive beyond this disease group.

trial registrationThis trial was initially registered with the NCI Clinical Trial Reporting Program ID: NCI-2021-03,567 on June 16, 2021. The study can be found on clinicaltrials.gov, Identifier NCT04928599 .

Indexed as

ParentsPrecursor Cell Lymphoblastic Leukemia-LymphomaAdaptation, PsychologicalAdolescentChildChild, PreschoolHumansInfantProspective StudiesSurveys and QuestionnairesUnited StatesChildhood allFinancial distressFinancial hardshipFinancial toxicityHealth outcomes

Identifiers

PMID35764995
PMCPMC9237978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.