ArticleBMC musculoskeletal disorders2022
Metal Artefact Reduction Sequences (MARS) in Magnetic Resonance Imaging (MRI) after Total Hip Arthroplasty (THA) : A non-invasive approach for preoperative differentiation between periprosthetic joint infection (PJI) and aseptic complications?
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Metal-artefact-reduction MRI for diagnosing periprosthetic joint infection: a systematic review and meta-analysis.Skeletal radiology · 2026Pooled it
- Quantifying the Long and Short Axes of the External Iliac Lymph Nodes Using Dual-Energy Computed Tomography: A Potential Diagnostic Approach for Periprosthetic Joint Infection - A Prospective Study.Infection and drug resistance · 2024Trial
- Outcomes of Surgical Strategies for Prosthetic Joint Infection Following Unicompartmental Knee Arthroplasty: A 2-Year Follow-up.Clinics in orthopedic surgery · 2026Article
- Acetabular cup anteversion measurement in total hip arthroplasty: reliability of metal artifact reduction MRI compared with CT.Skeletal radiology · 2026Article
- Magnetic Resonance-Based Determination of Local Tissue Infection Involvement in Patients with Periprosthetic Joint Infection Following Total Hip Arthroplasty.Journal of clinical medicine · 2026Article
- Response to the letter: "deep learning-driven knee MRI acceleration: evidence, enhancements, and the path to universal adoption".La Radiologia medica · 2025Article
- Machine Learning Strategies for Preoperative PJI Diagnosis: Integrative Analysis of Serum and Synovial Fluid Markers.Journal of inflammation research · 2025Article
- Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review.Microorganisms · 2024Review
- Postoperative Imaging of Bone and Soft Tissue Tumors in the Extremity: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- The role of advanced metal artifact reduction MRI in the diagnosis of periprosthetic joint infection.Skeletal radiology · 2024Review
- MRI of total hip arthroplasty: technical aspects and imaging findings.Insights into imaging · 2024Review
- An overview of the current diagnostic approach to Periprosthetic Joint Infections.Orthopedic reviews · 2024Article
- MRI-based artificial intelligence to predict infection following total hip arthroplasty failure.La Radiologia medica · 2023Article
- Roles of inflammatory cell infiltrate in periprosthetic osteolysis.Frontiers in immunology · 2023Review
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8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the past, radiographic imaging was of minor relevance in the diagnosis of periprosthetic joint infections (PJI). Since metal artefact reduction sequences (MARS) are available, magnetic resonance imaging (MRI) has become a promising diagnostic tool for the evaluation of hip arthroplasty implants. The purpose of the present study was to evaluate the efficacy of MARS-MRI in comparison to established diagnostic tools to distinguish between aseptic failure and PJI.
methodsFrom July 2018 to September 2019, 33 patients classified as having an aseptic joint effusion were recruited into the study. The group included 22 women and 11 men with a mean age of 70.4 ± 13.7 (42-88) years. In the same period, 12 patients were classified as having a PJI. The group consisted of 9 women and 3 men with a mean age of 72.5 ± 10.6 (54-88) years. MARS-MRI was conducted using the optimized parameters at 1.5 T in a coronal and axial STIR (short-tau-inversion recovery), a non-fat-saturated T2 in coronal view and a non-fat-saturated T1 in transverse view in 45 patients with painful hip after total hip arthroplasty (THA). Normally distributed continuous data were shown as mean ± standard deviation (SD) and compared using student's t-test. Non-normally distributed continuous data were shown as mean and compared using the Mann-Whitney U test.
resultsSynovial layering and muscle edema were significant features of periprosthetic joint infection, with sensitivities of 100% and specifities of 63.0-75.0%. The combined specifity and sensitivity levels of synovial layering and muscular edema was 88.0% and 90.0%. Granulomatous synovitis was a significant feature for aseptic failure, with 90.0% sensitivity and 57.0% specifity.
conclusionMARS-MRI is as suitable as standard diagnostic tools to distinguish between aseptic failure and PJI in patients with THA. Further studies with larger patient numbers have to prove whether MARS-MRI could be integral part of PJI diagnostic.
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