ArticleBMC pregnancy and childbirth2022
Analysis of the risk of complications during pregnancy in pregnant women with assisted reproductive technology: a retrospective study using registry linkage from 2013 to 2018 in Shanghai, China.
Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Prevalence of placenta previa among deliveries: An update systematic review and meta-analysis after the introduction of the two-child policy in Mainland China.Journal of global health · 2024Pooled it
- [Analysis of Maternal Pregnancy Characteristics and Adverse Neonatal Birth Outcomes at a Single Center From 2017 to 2022].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Association between assisted reproductive technology and gestational diabetes mellitus: the role of serum folate and triglycerides.Nutrition & diabetes · 2026Observational
- Analysis of factors that increase serum progesterone levels on the day of hCG administration in gonadotropin-releasing hormone antagonist cycles.Frontiers in endocrinology · 2026Article
- Association betweenFrontiers in endocrinology · 2026Article
- Risk Factors for Gestational Diabetes Mellitus in Mainland China: A Systematic Review and Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Effect of ART treatments on maternal and neonatal outcomes in singleton live births: A large-scale retrospective cohort study.Heliyon · 2024Article
- Impact of Systemic Lupus Erythematosus on Conception: Insights into Infertility, Fertility Preservation, Assisted Reproductive Technology, and Pregnancy Outcomes.Seminars in reproductive medicine · 2024Review
- A mutual comparison of pregnancy outcomes between different conception modes: a propensity score matching based retrospective cohort study.Frontiers in endocrinology · 2024Article
- Perinatal complications and neonatal outcomes inFrontiers in endocrinology · 2024Article
- Fertility treatment increases the risk of preterm birth independent of multiple gestations.F&S reports · 2023Article
- Secular trends of low birth weight, preterm birth, and small for gestational age in Shanghai from 2004 to 2020: an age-period-cohort analysis.BMC pregnancy and childbirth · 2023Article
- Incidence of complications amongJournal of medicine and life · 2023Article
- Uterine Nodal expression supports maternal immunotolerance and establishment of the FOXP3Frontiers in immunology · 2023Article
- Association between Abortion History and Perinatal and Neonatal Outcomes of Singleton Pregnancies after Assisted Reproductive Technology.Journal of clinical medicine · 2022Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the differences in pregnancy outcomes between assisted reproductive technology (ART) patients and natural pregnant women in Shanghai, China in the past 6 years objectively. And to assess the feasibility of the research method of registry-database linkage in mainland China.
methodsThis retrospective study was conducted using registry-database linkage. A total of 8102 pregnancies with ART and 8096 parturients with spontaneous conception (SC) from 10 reproductive centers and 111 hospitals composed our retrospective study. The primary outcomes were the rates of obstetric complications (pregnancy-induced hypertention [PIH], gestational diabetes mellitus [GDM], placenta previa, mode of delivery, preterm birth [PTB], low birth weight [LBW], and macrosomia). The prenatal outcomes were compared between ART and SC parturients, frozen-thawed embryo transfer (FET) and fresh embryo transfer, and in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). We calculated odds ratios (ORs) and 95% confidence intervals (CIs).
resultsThe final matching rate of the target population was 92% by using registry linkage. ART resulted in a higher rate of multiple birth, PTB, LBW, cesarean section, placenta previa and GDM compared with SC in the singleton cohort. In ART patients, pregnant women with FET had a significantly higher risk of PIH than those with fresh embryo transfer (14.1% Vs 9.3%, AOR1.528, 95% CI 1.303-1.793), but there was no difference between IVF and ICSI. FET is also related to the severity of PIH.
conclusionsART increased the rate of complications during pregnancy, the risk and severity of PIH in patients with FET was higher than that in patients with fresh embryo transfer. The registry-database linkage study is an objective and feasible research method in mainland China.
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