ArticleBMC primary care2022
Trends in the epidemiology of depression and comorbidities from 2000 to 2019 in Belgium.
Article in BMC primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of fluoxetine on body weight, waist circumference, and body mass index in individuals who are overweight or have obesity: a meta-analysis of randomized controlled trials.International journal of obesity (2005) · 2025Pooled it
- The impact of short-term ambient air pollution on CPAP therapy outcomes in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2026Article
- Development, Feasibility, and Appreciation of the Collaborative Integrated Depression Care (IDECA) Project in Flanders, Belgium.Journal of clinical medicine · 2026Article
- First-incidence of common mental disorders now and 12 years ago: Results from the Netherlands Mental Health Survey and Incidence Studies (NEMESIS).European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Assessment of the beneficial effects ofFrontiers in neuroscience · 2026Article
- The Art of Nanoimmunobiotechnomedicine in Depression Management.Advanced pharmaceutical bulletin · 2025Review
- Data resource profile: the Intego-II primary care database.International journal of epidemiology · 2025Article
- Close to the border-Resilience in healthcare in a European border region: Findings of a needs analysis.PloS one · 2025Article
- Visual analysis of research hotspots and trends of external therapies in traditional Chinese medicine for depression.Heliyon · 2024Article
- [Changes in the perception of benefits and risks of antidepressive pharmacotherapy].Der Nervenarzt · 2024Review
- Healthcare providers' perception of caring for older patients with depression and physical multimorbidity: insights from a focus group study.BMC primary care · 2024Article
- Prescriptions of antidepressants and anxiolytics in France 2012-2022 and changes with the COVID-19 pandemic: interrupted time series analysis.BMJ mental health · 2024Article
- The Integration of Clinical Decision Support Systems Into Telemedicine for Patients With Multimorbidity in Primary Care Settings: Scoping Review.Journal of medical Internet research · 2023Article
- Trends in the registration of anxiety in Belgian primary care from 2000 to 2021: a registry-based study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Article
- Depression in Heart Failure with Reduced Ejection Fraction, an Undervalued Comorbidity: An Up-To-Date Review.Medicina (Kaunas, Lithuania) · 2023Review
- Integrated Care Models for Older Adults with Depression and Physical Comorbidity: A Scoping Review.International journal of integrated careArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression is a common mental disorder in family practice with an impact on global health. The aim of this study is to provide insight in the trends of epidemiological measures as well as pharmacological treatments and comorbidities of depression.
methodsA study using data from INTEGO, a family practice registration network in Flanders, Belgium. Trends in age-standardized prevalence and incidence of depression from 2000 to 2019 as well as antidepressant prescriptions in prevalent depression cases were analyzed with join point regression. Comorbidity profiles were explored using the Cochran-Armitage test and the Jonckheere-Terpstra test.
resultsWe identified 538 299 patients older than 15 years during the study period. We found an increasing trend in the age-standardized prevalence of depression from 6.73 % in 2000 to 9.20 % in 2019. For the incidence of depression, a decreasing trend was observed from 2000 to 2015 with an incidence of 9.42/1000 in 2000 and 6.89/1000 in 2015, followed by an increasing trend from 2015 to 2019 (incidence of 13.64/1000 in 2019). The average number of chronic diseases per patient with depression increased significantly during the study period (from 1.2 to 1.8), and the proportion of patients relative to the whole study population that received at least one antidepressant prescription per year increased between 2000 and 2019 from 26.44% to 40.16%.
conclusionsThe prevalence of depression increases while the incidence sharply rises, but only in recent years. Patients with depression tend to have more comorbidities, making a multi-faceted approach to these patients more important.
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