Evidence map›Paper›PMID 35764748›Full record

ReviewMolecular biology reports2022

Genome editing (CRISPR-Cas)-mediated virus resistance in potato (Solanum tuberosum L.).

Jagesh Kumar Tiwari, Jeevalatha A, Narendra Tuteja, S M Paul Khurana

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Strategies for plant-virus disease management from gene editing to nanotechnology.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jagesh Kumar Tiwari *ICAR-Central Potato Research Institute, Shimla, Himachal Pradesh, 171001, India. jageshtiwari@gmail.com.ORCID http://orcid.org/0000-0002-3936-1458
Jeevalatha A *ICAR-Indian Institute of Spices Research, Kozhikode, Kerala, 673012, India.
Narendra TutejaInternational Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Road, New Delhi, 110067, India.
S M Paul KhuranaAmity University, Gurgaon, Manesar, Haryana, 122413, India.
Central Potato Research Institute · INIndian Institute of Spices Research · INInternational Centre for Genetic Engineering and Biotechnology · IN

Funding

Indian Council of Agricultural Research CABin SchemeIndian Council of Agricultural Research ICAR-IASRIIndian Council of Agricultural Research New Delhi
6 · The paper itself

Abstract

Plant viruses are the major pathogens that cause heavy yield loss in potato. The important viruses are potato virus X, potato virus Y and potato leaf roll virus around the world. Besides these three viruses, a novel tomato leaf curl New Delhi virus is serious in India. Conventional cum molecular breeding and transgenics approaches have been applied to develop virus resistant potato genotypes. But progress is slow in developing resistant varieties due to lack of host genes and long breeding process, and biosafety concern with transgenics. Hence, CRISPR-Cas mediated genome editing has emerged as a powerful technology to address these issues. CRISPR-Cas technology has been deployed in potato for several important traits. We highlight here CRISPR-Cas approaches of virus resistance through targeting viral genome (DNA or RNA), host factor gene and multiplexing of target genes simultaneously. Further, advancement in CRISPR-Cas research is presented in the area of DNA-free genome editing, virus-induced genome editing, and base editing. CRISPR-Cas delivery, transformation methods, and challenges in tetraploid potato and possible methods are also discussed.

Indexed as

Plant VirusesSolanum tuberosumCRISPR-Cas SystemsGene EditingGenome, PlantPlant BreedingCRISPR/CasGenome editingPlantPotatoVirus resistance

Identifiers

PMID35764748
OpenAlexW4283691962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.