ArticleScientific reports2022
Prospective bidirectional associations between depression and chronic kidney diseases.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 31 citations in OpenAlex.
- Depression in chronic kidney disease and dialysis: A psychonephrology narrative review.World journal of nephrology · 2026Review
- Validation of the Arabic Version of Patient Health Questionnaire-9 in Omani and Yemeni Patients With Chronic Physical Diseases.International journal of methods in psychiatric research · 2026Article
- 25(OH)D modifies the relationship between depressive symptoms and chronic kidney disease in diabetic patients.International urology and nephrology · 2026Article
- Mental health and kidney disease.Nature reviews. Nephrology · 2026Review
- Psychiatric comorbidity of depression and anxiety in medical trainees: prevalence and predictors in Ecuador.BMC psychiatry · 2026Article
- Pregnancy complications and risk of cardiometabolic-renal conditions in 1.4 million women in England: longitudinal study.BMJ medicine · 2026Article
- Associations of serum creatinine and blood urea nitrogen with depressive symptoms among community-dwelling older adults in Guangzhou, China: a cross-sectional study.Frontiers in psychiatry · 2026Article
- Association of hepatorenal function biomarkers with depression risk in geriatric psychiatry inpatient: a hospital-based cross-sectional study.BMC geriatrics · 2025Article
- Elevated Pulse Pressure and Risk of Chronic Kidney Disease by Hypertension Status: A Longitudinal Study in Japanese Adults.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Integrated analysis identifies key genes underlying the bidirectional association between depression and renal failure.Scientific reports · 2025Article
- Analysis of the Status and Influencing Factors of Depression in Chinese Middle-Aged and Older Cancer Patients-Based on Empirical Evidence from the 2020 CHARLS Database.Healthcare (Basel, Switzerland) · 2025Article
- Inverse associations of the lifestyle critical 9 with cardiorenal syndrome: the mediating role of the dietary inflammatory index.Frontiers in nutrition · 2025Article
- Chronic diseases and depressive symptoms in China: a psychosocial mechanism perspective.Frontiers in public health · 2025Article
- Association between C-reactive protein-triglyceride glucose index and depressive symptoms in American adults: results from the NHANES 2005 to 2010.BMC psychiatry · 2024Article
- Relationships between sarcopenia, depressive symptoms, and the risk of cardiovascular disease in Chinese population.The journal of nutrition, health & aging · 2024Article
- Association between sedentary behavior and depression in US adults with chronic kidney disease: NHANES 2007-2018.BMC psychiatry · 2023Article
- Association between chronic diseases and depression in the middle-aged and older adult Chinese population-a seven-year follow-up study based on CHARLS.Frontiers in public health · 2023Article
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Authors and funding
3 authors at 3 institutions in 1 country.
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Abstract
Previous studies had reported the mutual relation between depression and chronic kidney diseases (CKD). This study aimed to investigate potential bidirectional relationships between depression and CKD. Participants more than 45 years from the China Health and Retirement Longitudinal Study (CHARLS) were included in present study. In study I, we tended to assess the association between baseline depression with the risk of subsequent CKD. In study II, we aimed to examine whether the onset of CKD could predict the development of depression. Multivariate logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) in study I and study II, respectively. In study I, 301 (6.16%) respondents experienced CKD in participants without depression, and 233 (8.48%) respondents experienced CKD in participants with depression. Participants with depression had higher risk of developing CKD with the corresponding ORs (95% CIs) was 1.38(1.08-1.76). In study II, 1333 (22.29%) subjects in the non-CKD group and 97 (27.17%) in CKD group developed depressive symptoms. Individuals with CKD had higher risk of developing depression than those without CKD, with the multivariate ORs (95% CIs) was 1.48(1.23-1.78). Significant bidirectional relationships remained in both sensitivity and subgroup analyses. Findings demonstrate bidirectional relationships between depression and CKD. Individuals with depression were associated with increasing risk of CKD; in addition, CKD patients had higher risk of developing depression.
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