Evidence map›Paper›PMID 35763758›Full record

ArticleJMIR formative research2022

The Prevalence of Psychotic Symptoms, Violent Ideation, and Disruptive Behavior in a Population With SARS-CoV-2 Infection: Preliminary Study.

Sumra Bari, Nicole L Vike, Khrystyna Stetsiv, Sean Woodward, Shamal Lalvani, Leandros Stefanopoulos, Byoung Woo Kim, Nicos Maglaveras, Hans C Breiter, Aggelos K Katsaggelos

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sumra Bari *Department of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-2406-2463
Nicole L Vike *Department of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-8617-2377
Khrystyna StetsivDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-7816-1766
Sean WoodwardDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-8783-1039
Shamal LalvaniDepartment of Electrical and Computer Engineering, Northwestern University, Evanston, IL, United States.ORCID https://orcid.org/0000-0002-2677-8019
Leandros StefanopoulosLaboratory of Medical Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-2682-5639
Byoung Woo KimDepartment of Psychiatry and Behavioral Sciences, Northwestern University, Chicago, IL, United States.ORCID https://orcid.org/0000-0001-7612-4833
Nicos MaglaverasLaboratory of Medical Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-4919-0664
Hans C BreiterLaboratory of Neuroimaging and Genetics, Division of Psychiatric Neuroscience, Massachusetts General Hospital, Charlestown, MA, United States.ORCID https://orcid.org/0000-0002-4385-2778
Aggelos K KatsaggelosDepartment of Electrical and Computer Engineering, Northwestern University, Evanston, IL, United States.ORCID https://orcid.org/0000-0003-4554-0070
Northwestern University · USAristotle University of Thessaloniki · GRMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 disease results from infection by the SARS-CoV-2 virus to produce a range of mild to severe physical, neurological, and mental health symptoms. The COVID-19 pandemic has indirectly caused significant emotional distress, triggering the emergence of mental health symptoms in individuals who were not previously affected or exacerbating symptoms in those with existing mental health conditions. Emotional distress and certain mental health conditions can lead to violent ideation and disruptive behavior, including aggression, threatening acts, deliberate harm toward other people or animals, and inattention to or noncompliance with education or workplace rules. Of the many mental health conditions that can be associated with violent ideation and disruptive behavior, psychosis can evidence greater vulnerability to unpredictable changes and being at a greater risk for them. Individuals with psychosis can also be more susceptible to contracting COVID-19 disease.

objectiveThis study aimed to investigate whether violent ideation, disruptive behavior, or psychotic symptoms were more prevalent in a population with COVID-19 and did not precede the pandemic.

methodsIn this preliminary study, we analyzed questionnaire responses from a population sample (N=366), received between the end of February 2021 and the start of March 2021 (1 year into the COVID-19 pandemic), regarding COVID-19 illness, violent ideation, disruptive behavior, and psychotic symptoms. Using the Wilcoxon rank sum test followed by multiple comparisons correction, we compared the self-reported frequency of these variables for 3 time windows related to the past 1 month, past 1 month to 1 year, and >1 year ago among the distributions of people who answered whether they tested positive or were diagnosed with COVID-19 by a clinician. We also used multivariable logistic regression with iterative resampling to investigate the relationship between these variables occurring >1 year ago (ie, before the pandemic) and the likelihood of contracting COVID-19.

resultsWe observed a significantly higher frequency of self-reported violent ideation, disruptive behavior, and psychotic symptoms, for all 3 time windows of people who tested positive or were diagnosed with COVID-19 by a clinician. Using multivariable logistic regression, we observed 72% to 94% model accuracy for an increased incidence of COVID-19 in participants who reported violent ideation, disruptive behavior, or psychotic symptoms >1 year ago.

conclusionsThis preliminary study found that people who reported a test or clinician diagnosis of COVID-19 also reported higher frequencies of violent ideation, disruptive behavior, or psychotic symptoms across multiple time windows, indicating that they were not likely to be the result of COVID-19. In parallel, participants who reported these behaviors >1 year ago (ie, before the pandemic) were more likely to be diagnosed with COVID-19, suggesting that violent ideation, disruptive behavior, in addition to psychotic symptoms, were associated with COVID-19 with an approximately 70% to 90% likelihood.

Indexed as

COVID-19delusionsdisruptive behaviordistressmachine learningmental healthpandemicparanoiapsychological healthpsychosispsychotic symptomsriskstressviolent ideation

Identifiers

PMID35763758
PMCPMC9384857
OpenAlexW4283707779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.