ArticleAsian Pacific journal of cancer prevention : APJCP2022
Health-Related Quality of Life of Patients with Cervical Cancer According to the Duration of Treatment and Cancer Progression.
Article in Asian Pacific journal of cancer prevention : APJCP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Health-related quality of life in patients with cervical cancer: a systematic review and meta-analysis of EQ‑5D utility scores.Scientific reports · 2026Pooled it
- Global Prevalence of Chronic Pain Among Cancer Survivors: A Systematic Review and Proportional Meta-Analysis of Observational Studies.Worldviews on evidence-based nursing · 2026Pooled it
- Article
- Validity of HINT-8 in evaluating health-related quality of life among cervical cancer patients.Journal of comparative effectiveness research · 2026Article
- Factors Affecting Quality of Life of Thai Cervical Cancer Patients.The journal of obstetrics and gynaecology research · 2026Article
- Factors affecting health-related quality of life in cervical cancer survivors: a multicenter cross-sectional study in Korea.BMC women's health · 2026Observational
- Using Machine Learning to Predict the Prognosis of Cervical Cancer Patients with Lymph Node Metastasis: An Analysis Based on the SEER Database.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Clinical and prognostic outcomes of colposcopy-guided LEEP versus cold knife conization in the management of cervical intraepithelial neoplasia.Frontiers in oncology · 2025Article
- The psychometric properties of the amharic version of EuroQoL five-dimensions-five level among Ethiopian cervical cancer patients.Health and quality of life outcomes · 2024Article
- Atezolizumab plus bevacizumab and chemotherapy as first-line therapy for cervical cancer: a cost-effectiveness analysis in the US.Frontiers in immunology · 2024Article
- Clinical analysis of decision implementation by a multidisciplinary team in cervical cancer cases in Ganzhou, China.Frontiers in oncology · 2023Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to assess health-related quality of life (HRQoL) in Korean patients with cervical cancer according to the duration of treatment and cancer progression of cervical cancer.
methodsThis study included 452 outpatients with cervical intraepithelial neoplasia (CIN) or invasive cervical cancer from six tertiary hospitals in South Korea. The questionnaire included the EQ-5D-3L instrument, patients' age, cancer progression (CIN or invasive cervical cancer), treatment duration (<1 year, ≥1 year but <2 years, and ≥2 years), treatment method (surgery, chemotherapy, radiation therapy), and presence of recurrence. HRQoL indices were calculated for these independent factors, and the mean was compared using ANOVA. Multiple regression analysis was performed to analyze factors affecting HRQoL in patients with cervical cancer.
resultsThe EQ-5D index was 0.93 for patients with CIN, 0.87 for patients with invasive cervical cancer, and 0.78 for patients with recurrent invasive cervical cancer. HRQoL was significantly lower as the CIN progresses to cervical cancer. HRQoL of patients with invasive cervical cancer was lowest within 1 year of treatment in all stages. In addition, the HRQoL of patients with CIN or invasive cervical cancer who received chemotherapy and radiotherapy was lower than that of patients who underwent surgery. Multiple regression analysis showed that the HRQoL decreased significantly as increasing age, the first year of treatment after diagnosis, cancer recurrence, or chemotherapy.
conclusionThe HRQoL of patients with cervical cancer is affected not only by the stage of cancer progression but also by the duration of treatment and the type of treatment. As a result, when trying to apply the quality of life of patients with cervical cancer to cost-utility analysis, it is necessary to consider the duration and the type of treatment they receive.
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