Evidence map›Paper›PMID 35763502›Full record

ArticlePloS one2022

Impact of acute temperature and air pollution exposures on adult lung function: A panel study of asthmatics.

Richard Evoy, Laurel Kincl, Diana Rohlman, Lisa M Bramer, Holly M Dixon, Perry Hystad, Harold Bae, Michael Barton, Aaron Phillips, Rachel L Miller and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Characterizing variability in personal chemical exposure to improve exposomics.Journal of exposure science & environmental epidemiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. PMGeoHealth · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Richard EvoyCollege of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, United States of America.ORCID 0000-0002-5201-8427
Laurel KinclCollege of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, United States of America.
Diana RohlmanCollege of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, United States of America.
Lisa M BramerBiological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, United States of America.ORCID 0000-0002-8384-1926
Holly M DixonEnvironmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon, United States of America.
Perry HystadCollege of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, United States of America.
Harold BaeCollege of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon, United States of America.
Michael BartonEnvironmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon, United States of America.
Aaron PhillipsComputing & Analytics Division, Pacific Northwest National Laboratory, Richland, Washington, United States of America.
Rachel L MillerIcahn School of Medicine at Mount Sinai, New York City, New York, United States of America.
Katrina M WatersSuperfund Research Program, Oregon State University, Corvallis, Oregon, United States of America.
Julie B HerbstmanEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York City, New York, United States of America.
Kim A AndersonSuperfund Research Program, Oregon State University, Corvallis, Oregon, United States of America.
Oregon State University · USPacific Northwest National Laboratory · USColumbia University · USIcahn School of Medicine at Mount Sinai · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Robyn L Tanguay · 2009 to 2026
$52.5M
Reducing Susceptibility to Environmental Stress Throughout the Life SpanP30ES000210 · NIEHS · OREGON STATE UNIVERSITY · PI BECKMAN, JOSEPH S · 1985 to 2015
$21.4M
MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
Personal Envl Exposure Assmt using Wristbands for Epi Studies in Disadv CommR33ES024718 · NIEHS · OREGON STATE UNIVERSITY · PI ANDERSON, KIM A., HERBSTMAN, JULIE BETH · 2016 to 2019
$2.3M
NIEHS NIH HHS P30 ES000210NIEHS NIH HHS P42 ES016465NIEHS NIH HHS R33 ES024718NIEHS NIH HHS T32 ES007060
6 · The paper itself

Abstract

backgroundIndividuals with respiratory conditions, such as asthma, are particularly susceptible to adverse health effects associated with higher levels of ambient air pollution and temperature. This study evaluates whether hourly levels of fine particulate matter (PM2.5) and dry bulb globe temperature (DBGT) are associated with the lung function of adult participants with asthma. METHODS AND

findingsGlobal positioning system (GPS) location, respiratory function (measured as forced expiratory volume at 1 second (FEV1)), and self-reports of asthma medication usage and symptoms were collected as part of the Exposure, Location, and Lung Function (ELF) study. Hourly ambient PM2.5 and DBGT exposures were estimated by integrating air quality and temperature public records with time-activity patterns using GPS coordinates for each participant (n = 35). The relationships between acute PM2.5, DBGT, rescue bronchodilator use, and lung function collected in one week periods and over two seasons (summer/winter) were analyzed by multivariate regression, using different exposure time frames. In separate models, increasing levels in PM2.5, but not DBGT, were associated with rescue bronchodilator use. Conversely DBGT, but not PM2.5, had a significant association with FEV1. When DBGT and PM2.5 exposures were placed in the same model, the strongest association between cumulative PM2.5 exposures and the use of rescue bronchodilator was identified at the 0-24 hours (OR = 1.030; 95% CI = 1.012-1.049; p-value = 0.001) and 0-48 hours (OR = 1.030; 95% CI = 1.013-1.057; p-value = 0.001) prior to lung function measure. Conversely, DBGT exposure at 0 hours (β = 3.257; SE = 0.879; p-value>0.001) and 0-6 hours (β = 2.885; SE = 0.903; p-value = 0.001) hours before a reading were associated with FEV1. No significant interactions between DBGT and PM2.5 were observed for rescue bronchodilator use or FEV1.

conclusionsShort-term increases in PM2.5 were associated with increased rescue bronchodilator use, while DBGT was associated with higher lung function (i.e. FEV1). Further studies are needed to continue to elucidate the mechanisms of acute exposure to PM2.5 and DBGT on lung function in asthmatics.

Indexed as

Air PollutionAsthmaAdultBronchodilator AgentsEnvironmental ExposureHumansLungTemperatureBronchodilator Agents

Identifiers

PMID35763502
PMCPMC9239441
OpenAlexW4283647276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.