Evidence map›Paper›PMID 35763380›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Impairment of the NKT-STAT1-CXCL9 Axis Contributes to Vessel Fibrosis in Pulmonary Hypertension Caused by Lung Fibrosis.

Katharina Jandl, Leigh M Marsh, Ayse Ceren Mutgan, Slaven Crnkovic, Francesco Valzano, Diana Zabini, Julia Hoffmann, Vasile Foris, Elisabeth Gschwandtner, Walter Klepetko and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 55 citations in OpenAlex.

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  7. The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Article
  9. Signaling pathways and targeted therapy for pulmonary hypertension.Signal transduction and targeted therapy · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Katharina JandlLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Leigh M MarshLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Ayse Ceren MutganLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Slaven CrnkovicLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Francesco ValzanoLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Diana ZabiniLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Julia HoffmannLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Vasile ForisLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Elisabeth GschwandtnerDepartment of Surgery and.
Walter KlepetkoDepartment of Surgery and.
Helmut ProschDepartment of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.
Holger FlickDivision of Pulmonology, Department of Internal Medicine, and.
Luka BrcicDiagnostic and Research Center for Molecular BioMedicine, Diagnostic & Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Izidor KernCytology and Pathology Laboratory, University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia; and.
Akos HeinemannDivision of Pharmacology.
Horst OlschewskiLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.ORCID 0000-0002-2834-7466
Gabor KovacsLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Grazyna KwapiszewskaLudwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
Ludwig Boltzmann Institute for Lung Vascular Research · ATMedical University of Graz · ATMedical University of Vienna · ATUniversity Clinic of Pulmonary and Allergic Diseases Golnik · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryLung Diseases, InterstitialPulmonary FibrosisAnimalsChemokine CXCL9CollagenHumansInterleukin-15Leukocytes, MononuclearMiceNatural Killer T-CellsSTAT1 Transcription FactorChemokine CXCL9CollagenCXCL9 protein, humanInterleukin-15STAT1 protein, humanStat1 protein, mouseSTAT1 Transcription Factorimmunotherapyinterstitial lung diseasevascular fibrosisvascular remodeling

Identifiers

PMID35763380
OpenAlexW4283705362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.