Evidence map›Paper›PMID 35763158›Full record

ArticleBreast cancer research and treatment2022

Surgical margin status and survival outcomes of breast cancer patients treated with breast-conserving surgery and whole-breast irradiation after neoadjuvant chemotherapy.

Jong-Ho Cheun, Young Joo Lee, Jun-Hee Lee, Yungil Shin, Jung Whan Chun, Soo Yeon Baek, Hong-Kyu Kim, Han-Byoel Lee, Jonghan Yu, Byung Joo Chae and 2 more

Abstract read
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Article in Breast cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jong-Ho Cheun *Division of Breast Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Young Joo Lee *Division of Breast Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Jun-Hee Lee *Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Yungil ShinDivision of Breast Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Jung Whan ChunDivision of Breast Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Soo Yeon BaekDivision of Breast Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Hong-Kyu KimDivision of Breast Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Han-Byoel LeeDivision of Breast Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Jonghan YuDivision of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Byung Joo ChaeDivision of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Wonshik HanDivision of Breast Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Jeong Eon LeeDivision of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. jeongeon.lee@samsung.com.ORCID http://orcid.org/0000-0003-0037-2456
Seoul National University · KRUlsan College · KRSamsung Medical Center · KRSoonchunhyang University Hospital Seoul · KR

Funding

Ministry of Science and ICT (MIST) IITP-2020-0-01821National Research Foundation of Korea 2018R1D1A1A09081884SMC-SKKU Future Convergence Program Grant SMO1190341
6 · The paper itself

Abstract

purposeThe definition of "no tumor on ink" is generally applied for clear resection margin (RM) after breast-conserving surgery (BCS). However, few studies reported the effect of RM in the setting of neoadjuvant chemotherapy (NAC). We investigated the association between RM status and survival outcomes for those who underwent BCS after NAC for breast cancer.

methodsWe retrospectively reviewed the data of 2,803 patients who underwent BCS and whole-breast irradiation after NAC between January 2008 and December 2016 from three institutions in South Korea.

resultsThe 786 patients in the pathologic complete response group (R

conclusionClear RM of specimen does not have benefit on LRFS after NAC. Additionally, for the patients showing pCR with residual DCIS in the breast, margin involvement also did not affect the risk of local recurrence.

Indexed as

Breast NeoplasmsCarcinoma, Intraductal, NoninfiltratingFemaleHumansMargins of ExcisionMastectomy, SegmentalNeoadjuvant TherapyNeoplasm Recurrence, LocalPrognosisRetrospective StudiesBreast neoplasmsMargins of excisionMastectomy, segmentalNeoplasm recurrence, local

Identifiers

PMID35763158
OpenAlexW4283656411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.