Evidence map›Paper›PMID 35762780›Full record

ArticleMicrobiology spectrum2022

Screening Host Antiviral Proteins under the Enhanced Immune Responses Induced by a Variant Strain of Porcine Epidemic Diarrhea Virus.

Min Sun, Zeyanqiu Yu, Miao Luo, Bin Li, Zihao Pan, Jiale Ma, Huochun Yao

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Min SunInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Zeyanqiu YuCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Miao LuoCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Bin LiInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.ORCID 0000-0003-1318-7081
Zihao PanCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Jiale MaCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-2163-9247
Huochun YaoCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-3749-8557
Nanjing Agricultural University · CNJiangsu Academy of Agricultural Sciences · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While discussing the ideal candidates of viral restriction factor, the interferon (IFN) and interferon-stimulated genes (ISGs) could be considered potential targets. However, numerous viruses have evolved multiple strategies to modulate the host innate immune signaling for optimal infection, including the porcine epidemic diarrhea virus (PEDV), a coronavirus spreading widely around the world with high morbidity and mortality in piglets. The immunosuppression mediated by PEDV infection creates an impediment for studying the host-virus interactions and screening the antiviral ISGs. Here, the PEDV variant strain 85-7

Indexed as

Coronavirus InfectionsPorcine epidemic diarrhea virusAnimalsAntiviral AgentsCell LineImmunity, InnateInterferonsSwineAntiviral AgentsInterferonsIFI44IFNimmune-enhanced variantOASLporcine epidemic diarrhea virustranscriptomics

Identifiers

PMID35762780
PMCPMC9430966
OpenAlexW4283661895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.