ArticleDevelopment (Cambridge, England)2022
The pseudobranch of jawed vertebrates is a mandibular arch-derived gill.
Article in Development (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- Shared competence forms the basis of gill arch and paired fin serial homology.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The skate spiracular organ develops from a unique neurogenic placode that is distinct from lateral line placodes.Development (Cambridge, England) · 2025Article
- Article
- Pre-mandibular pharyngeal pouches in early non-teleost fish embryos.Proceedings. Biological sciences · 2023Article
- Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
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Abstract
The pseudobranch is a gill-like epithelial elaboration that sits behind the jaw of most fishes. This structure was classically regarded as a vestige of the ancestral gill arch-like condition of the gnathostome jaw. However, more recently, hypotheses of jaw evolution by transformation of a gill arch have been challenged, and the pseudobranch has alternatively been considered a specialised derivative of the second (hyoid) pharyngeal arch. Here, we demonstrate in the skate (Leucoraja erinacea) that the pseudobranch does, in fact, derive from the mandibular arch, and that it shares gene expression features and cell types with gills. We also show that the skate mandibular arch pseudobranch is supported by a spiracular cartilage that is patterned by a shh-expressing epithelial signalling centre. This closely parallels the condition seen in the gill arches, where cartilaginous appendages called branchial rays, which support the respiratory lamellae of the gills, are patterned by a shh-expressing gill arch epithelial ridge. Together with similar discoveries in zebrafish, our findings support serial homology of the pseudobranch and gills, and an ancestral origin of gill arch-like anatomical features from the gnathostome mandibular arch.
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