Evidence map›Paper›PMID 35762608›Full record

ArticleAnnals of surgery2023

Mid-term Surgery Outcomes in Patients With COVID-19: Results From a Nationwide Analysis.

Nikhil K Prasad, Minerva Mayorga-Carlin, Shalini Sahoo, Brian R Englum, Douglas J Turner, Tariq Siddiqui, Rachel Lake, John D Sorkin, Brajesh K Lal

Abstract read
In one paragraph

Article in Annals of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Impact of COVID-19 on Opioid Prescribing, Consumption, Pain, and Outcomes after Surgery.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nikhil K PrasadDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Minerva Mayorga-CarlinDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Shalini SahooDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Brian R EnglumDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Douglas J TurnerDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Tariq SiddiquiSurgery Service, Veterans Affairs Medical Centre, Baltimore, MD.
Rachel LakeDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.
John D SorkinGeriatrics Research, Education, and Clinical Center, Veterans Affairs Medical Centre, Baltimore, MD.
Brajesh K LalDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD.

Funding

CREST-2 Clinical Coordinating CenterU01NS080168 · NINDS · MAYO CLINIC JACKSONVILLE · PI Thomas G Brott, JAMES F MESCHIA · 2014 to 2026
$56.3M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Carotid Revascularization and Medical Management for Asymptomatic CarotidStenosis Trial - Hemodynamics (CREST-H)R01NS097876 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RONALD M LAZAR, DAVID SIGMUND LIEBESKIND · 2017 to 2026
$6.4M
Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates - 2I01CX001621 · VA · BALTIMORE VA MEDICAL CENTER · PI LAL, BRAJESH K · 2017 to 2021
–
Role of a Novel Exercise Program to Prevent Post-thrombotic SyndromeI01RX000995 · VA · BALTIMORE VA MEDICAL CENTER · PI LAL, BRAJESH K · 2015 to 2020
–
CSRD VA I01 CX001621Intramural NIH HHS Z01 AG000513NIA NIH HHS P30 AG028747NIA NIH HHS T32 AG000262NIDDK NIH HHS P30 DK072488NINDS NIH HHS R01 NS097876NINDS NIH HHS U01 NS080168RRD VA I01 RX000995
6 · The paper itself

Abstract

objectiveDetermine mid-term postoperative outcomes among coronavirus disease 2019 (COVID-19)-positive (+) patients compared with those who never tested positive before surgery.

backgroundCOVID-19 is thought to be associated with prohibitively high rates of postoperative complications. However, prior studies have only evaluated 30-day outcomes, and most did not adjust for demographic, clinical, or procedural characteristics.

methodsWe analyzed data from surgeries performed at all Veterans Affairs hospitals between March 2020 and 2021. Kaplan-Meier curves compared trends in mortality and Cox proportional hazards models estimated rates of mortality and pulmonary, thrombotic, and septic postoperative complications between patients with a positive preoperative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test [COVID (+)] and propensity score-matched COVID-negative (-) patients.

resultsOf 153,741 surgical patients, 4778 COVID (+) were matched to 14,101 COVID (-). COVID (+) status was associated with higher postoperative mortality ( P <0.0001) with a 6-month survival of 94.2% (95% confidence interval: 93.2-95.2) versus 96.0% (95% confidence interval: 95.7.0-96.4) in COVID (-). The highest mortality was in the first 30 postoperative days. Hazards for mortality and postoperative complications in COVID (+) decreased with increasing time between testing COVID (+) and date of surgery. COVID (+) patients undergoing elective surgery had similar rates of mortality, thrombotic and septic complications, but higher rates of pulmonary complications than COVID (-) patients.

conclusionsThis is the first report of mid-term outcomes among COVID-19 patients undergoing surgery. COVID-19 is associated with decreased overall and complication-free survival primarily in the early postoperative period, delaying surgery by 5 weeks or more reduces risk of complications. Case urgency has a multiplicative effect on short-term and long-term risk of postoperative mortality and complications.

Indexed as

COVID-19Elective Surgical ProceduresHumansPostoperative ComplicationsRetrospective StudiesSARS-CoV-2

Identifiers

PMID35762608
PMCPMC9794632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.