Evidence map›Paper›PMID 35762562›Full record

ArticleJournal of medical radiation sciences2022

Novel methodology to quantify dehydration in head and neck cancer radiotherapy using DIXON MRI.

Sophie Duncan, Amy Walker, Shivani Kumar, Kylie Dundas, Katherine Bell, Andrew Wallis, Yolanda Surjan, Farhannah Aly, Mark Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical radiation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sophie DuncanMedical Radiation Science (MRS), School of Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.ORCID https://orcid.org/0000-0003-3150-0553
Amy WalkerLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
Shivani KumarLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
Kylie DundasLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
Katherine BellDietetics Department, Liverpool Hospital, Sydney, New South Wales, Australia.
Andrew WallisLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
Yolanda SurjanMedical Radiation Science (MRS), School of Health Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.
Farhannah AlyLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
Mark LeeLiverpool and Macarthur Cancer Therapy Centres, Sydney, New South Wales, Australia.
UNSW Sydney · AUCancer Australia · AULiverpool Hospital · AUUniversity of Newcastle Australia · AUUniversity of Wollongong · AU

Funding

South Western Sydney Local Health District
6 · The paper itself

Abstract

introductionHead and neck cancer (HNC) patients are at risk of weight change, due to inadequate nutrition intake or dehydration, when receiving radiotherapy (RT). This study aimed to develop methodology to measure water content changes on magnetic resonance imaging (MRI) scans of the head and neck region over the course of RT.

methodsRetrospective datasets of 54 patients were analysed. Eligible patients had been treated for HNC with cisplatin chemoradiation (CRT) or RT alone and underwent a minimum of 2 MRI scans from weeks 0, 3 and 6 of their treatment. Anatomical regions consisting of ≥90% water, on T2-weighted DIXON MRI sequences, were contoured. Water volume changes of all patients were evaluated, within an anatomically standardised external volume, by comparing the absolute water fraction volume (cc) (VEx90WF) and relative water fraction volume (%) (RelVEx90WF) at weeks 0 and 6 of RT.

resultsThere was a statistically significant difference between the RelVEx90WF at weeks 0 and 6 (P = 0.005). However, no statistically significant difference was identified between weeks 0 and 6 VEx90WF (P = 0.064). There were no statistically significant differences identified between patients who received CRT versus RT alone.

conclusionThis study developed a novel method for measuring changes in water fraction volumes over time, using T2-weighted DIXON MRIs. The methodology created in this study requires further validation through phantom imaging, with known fat and water values.

Indexed as

DehydrationHead and Neck NeoplasmsHumansMagnetic Resonance ImagingRetrospective StudiesWaterWaterHead and Neck < Clinical SiteMagnetic Resonance Imaging < DisciplineRadiotherapy (Radiation Therapy) < Discipline

Identifiers

PMID35762562
PMCPMC9714511
OpenAlexW4283653879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.