Evidence map›Paper›PMID 35762367›Full record

ArticleThe Analyst2022

Simultaneous monitoring of HIV viral load and screening of SARS-CoV-2 employing a low-cost RT-qPCR test workflow.

Gaurav K Gulati, Nuttada Panpradist, Samuel W A Stewart, Ingrid A Beck, Ceejay Boyce, Amy K Oreskovic, Claudia García-Morales, Santiago Avila-Ríos, Peter D Han, Gustavo Reyes-Terán and 4 more

Open access · greenAbstract read
In one paragraph

Article in The Analyst, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Gaurav K GulatiDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.ORCID http://orcid.org/0000-0002-9825-2788
Nuttada PanpradistDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.ORCID http://orcid.org/0000-0002-2733-4110
Samuel W A StewartDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.
Ingrid A BeckCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Ceejay BoyceCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Amy K OreskovicDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.ORCID http://orcid.org/0000-0003-4911-4431
Claudia García-MoralesCentre for Research in Infectious Diseases of the National Institute of Respiratory Diseases (CIENI/INER), Mexico City, Mexico.ORCID http://orcid.org/0000-0002-3316-8761
Santiago Avila-RíosCentre for Research in Infectious Diseases of the National Institute of Respiratory Diseases (CIENI/INER), Mexico City, Mexico.ORCID http://orcid.org/0000-0003-3371-4248
Peter D HanDepartment of Genome Sciences, Seattle, WA, USA.
Gustavo Reyes-TeránCoordination of the Mexican National Institutes of Health and High Specialty Hospitals, Mexico City, Mexico.
Lea M StaritaDepartment of Genome Sciences, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2870-5099
Lisa M FrenkelCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Barry R LutzDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.ORCID http://orcid.org/0000-0003-4298-4901
James J LaiDepartment of Bioengineering, University of Washington, Seattle, Washington, USA. blutz@uw.edu.ORCID http://orcid.org/0000-0003-3437-7810
University of Washington · USInfectious Disease Research Institute · USBrotman Baty Institute · USMexican Social Security Institute · MX

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Diseases of Public Health Importance Training GrantT32AI007509 · NIAID · UNIVERSITY OF WASHINGTON · PI LUND, JENNIFER M · 1997 to 2024
$6.3M
V-OLA: point-of-care HIV viral load monitoring and drug resistance testingR01AI145486 · NIAID · UNIVERSITY OF WASHINGTON · PI Barry Ryan Lutz · 2019 to 2026
$5.6M
HIV-specific target capture and quantitative isothermal amplification for acute HIV diagnosis and treatment monitoringR33AI140460 · NIAID · UNIVERSITY OF WASHINGTON · PI LUTZ, BARRY RYAN · 2021 to 2022
$1.5M
HIV-specific target capture and quantitative isothermal amplification for acute HIV diagnosis and treatment monitoringR61AI140460 · NIAID · UNIVERSITY OF WASHINGTON · PI LUTZ, BARRY RYAN · 2018 to 2020
$1.4M
NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI064518NIAID NIH HHS R01 AI145486NIAID NIH HHS R33 AI140460NIAID NIH HHS R61 AI140460NIAID NIH HHS T32 AI007509
6 · The paper itself

Abstract

The COVID-19 pandemic interrupted routine care for individuals living with HIV, putting them at risk of virologic failure and HIV-associated illness. Often this population is at high risk for exposure to SARS-CoV-2 infection, and once infected, for severe disease. Therefore, close monitoring of HIV plasma viral load (VL) and screening for SARS-CoV-2 infection are needed. We developed a non-proprietary method to isolate RNA from plasma, nasal secretions (NS), or both. The extracted RNA is then submitted to RT-qPCR to estimate the VL and classify HIV/SARS-CoV-2 status (

Indexed as

COVID-19HIV InfectionsHumansPandemicsRNA, ViralSARS-CoV-2Sensitivity and SpecificityViral LoadWorkflowRNA, Viral

Identifiers

PMID35762367
PMCPMC10143869
OpenAlexW4283707134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.