Evidence map›Paper›PMID 35762278›Full record

ArticleBJU international2022

Nomogram predicting the probability of spontaneous stone passage in patients presenting with acute ureteric colic.

Chuanyu Gao, Max Peters, Piet Kurver, Thineskrishna Anbarasan, Keerthanaa Jayaraajan, Todd Manning, Sophia Cashman, Arjun Nambiar, Marcus Cumberbatch, Benjamin W Lamb and 6 more

Open access · hybridAbstract read
In one paragraph

Article in BJU international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  5. Observational
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  9. Renal colic imaging: Are we Choosing Wisely?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 4 countries.

Chuanyu GaoBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.ORCID https://orcid.org/0000-0002-9824-6468
Max PetersDepartment of Radiation Oncology, Cancer Centre, University Medical Centre Utrecht.
Piet KurverDepartment of Radiation Oncology, Cancer Centre, University Medical Centre Utrecht.
Thineskrishna AnbarasanBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.
Keerthanaa JayaraajanBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.
Todd ManningAustralian Young Urology Researchers Organisation (YURO), Australia.ORCID https://orcid.org/0000-0001-5609-3769
Sophia CashmanBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.
Arjun NambiarBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.
Marcus CumberbatchBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.ORCID https://orcid.org/0000-0001-5548-379X
Benjamin W LambBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.ORCID https://orcid.org/0000-0003-2220-893X
Robert PickardNewcastle University, Dept. of Urology, Newcastle, United Kingdom.
Paul ErotocritouWhittington Hospital, Dept. of Urology, London, United Kingdom.
Daron SmithUniversity College London Hospital, Dept. of Urology, London, United Kingdom.ORCID https://orcid.org/0000-0001-8314-4795
Veeru KasivisvanathanBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.
Taimur T ShahBritish Urology Researchers in Surgical Training (BURST), London, United Kingdom.ORCID https://orcid.org/0000-0003-1642-1208
BURST Collaborative MIMIC Study Group
British Association of Urological Surgeons · GBUniversity Medical Center Utrecht · NLAustralian Nuclear Science and Technology Organisation · AUCambridge University Hospitals NHS Foundation Trust · GBCharing Cross Hospital · GBCollaborative Group (United States) · USUniversity College Hospital · GBUniversity of Newcastle Australia · AUWhittington Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo develop a nomogram that could predict spontaneous stone passage (SSP) in patients presenting with acute ureteric colic who are suitable for conservative management. SUBJECT/PATIENTS: A 2517 patient dataset was utilised from an international multi-centre cohort study (MIMIC, A Multi-centre Cohort Study Evaluating the role of Inflammatory Markers In Patients Presenting with Acute Ureteric Colic) of patients presenting with acute ureteric colic across 71 secondary care hospitals in the United Kingdom, Ireland, Australia, and New Zealand. Inclusion criteria mandated a non-contrast CT-KUB.

methodsSSP was defined as the 'absence of the need for intervention'. The model was developed using logistic regression and backwards selection (to achieve lowest AIC) in a subset from 2009-2015 (n=1728) and temporally validated on a subset from 2016-2017 (n=789).

resultsOf the 2517 patients, 1874 had SSP (74.5%). Mean age (±[SD]) was 47 (±14.7) years and 1892 were male (75.2%). At the end of the modelling process, gender: male (OR 0.8, 95%CI 0.64-1.01, p=0.07), neutrophil count (OR 1.03, 95%CI 1.00-1.06, p = 0.08), hydronephrosis (OR 0.79, 95%CI 0.59-1.05, p=0.1), hydroureter (OR 1.3, 95%CI 0.97-1.75, p =0.08), stone size >5-7mm (OR 0.2, 95%CI 0.16-0.25, p<0.0001), stone size >7mm (OR 0.11, 95%CI 0.08-0.15, p<0.001), middle ureter stone position (OR 0.59, 95%CI 0.43-0.81, p=0.001), upper ureter stone position (OR 0.31, 95%CI 0.25-0.39, p<0.001) ), medical expulsive therapy use (OR 1.36, 95%CI 1.1 - 1.67, p = 0.001), oral NSAID use (OR 1.3, 95%CI 0.99 - 1.71, p=0.06), and rectal NSAID use (OR1.17, 95%CI 0.9 - 1.53, p=0.24) remained. Concordance-statistic (C-statistic) was 0.77 (95%CI 0.75 - 0.80) and a nomogram was developed based on these.

conclusionThe presented nomogram is available to use as an online calculator via www.BURSTurology.com and could allow clinicians and patients to make a more informed decision on pursuing conservative management versus early intervention.

Indexed as

multivariablenormogrampredictspontaneous stone passageUreteric colic

Identifiers

PMID35762278
PMCPMC9796920
OpenAlexW4283660777

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.