Evidence map›Paper›PMID 35762103›Full record

ArticleESC heart failure2022

The difference between cystatin C- and creatinine-based assessment of kidney function in acute heart failure.

Alberto Pinsino, Matteo Fabbri, Lorenzo Braghieri, Bruno Bohn, Antonia J Gaudig, Andrea Kim, Koji Takeda, Yoshifumi Naka, Gabriel T Sayer, Nir Uriel and 6 more

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Authors' Reply: Concerns about Hospitalization on Cystatin C- and Creatinine-Based eGFR.Journal of the American Society of Nephrology : JASN · 2025
    Article
  11. Differential Effect of Hospitalization on Cystatin C- and Creatinine-Based Estimated GFR.Journal of the American Society of Nephrology : JASN · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Alberto PinsinoDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Matteo FabbriDepartment of Medicine, NYC Health + Hospitals/Jacobi, Albert Einstein College of Medicine, Bronx, NY, USA.
Lorenzo BraghieriDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Bruno BohnDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
Antonia J GaudigWestfälische Wilhelms-Universität Münster, Munster, Germany.
Andrea KimDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Koji TakedaDepartment of Surgery, Division of Cardiac Surgery, Columbia University Irving Medical Center, New York, NY, USA.
Yoshifumi NakaDepartment of Surgery, Division of Cardiac Surgery, Columbia University Irving Medical Center, New York, NY, USA.
Gabriel T SayerDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Nir UrielDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Ryan T DemmerDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
Robert T FaillaceDepartment of Medicine, NYC Health + Hospitals/Jacobi, Albert Einstein College of Medicine, Bronx, NY, USA.
Syed A HusainDepartment of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, NY, USA.
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, NY, USA.
Paolo C ColomboDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Melana YuzefpolskayaDepartment of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · USJacobi Medical Center · USMinnesota Department of Health · USMontefiore Medical Center · USUniversity of Minnesota · USUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAcute heart failure (HF) is associated with muscle mass loss, potentially leading to overestimation of kidney function using serum creatinine-based estimated glomerular filtration rate (eGFR METHODS AND

resultsA post hoc analysis was performed in 841 patients enrolled in three trials: Diuretic Optimization Strategy Evaluation (DOSE), Renal Optimization Strategies Evaluation (ROSE), and Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARRESS-HF). Intra-individual differences between eGFRs (eGFR

conclusionsIn acute HF, a marked difference between eGFR

Indexed as

Cystatin CHeart FailureCreatinineGlomerular Filtration RateHumansKidneyCreatinineCystatin CAcute heart failureCardiorenal syndromeCystatin CGlomerular filtration rate

Identifiers

PMID35762103
PMCPMC9715858
OpenAlexW4283651429

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.