Evidence map›Paper›PMID 35761945›Full record

ArticleOncology letters2022

B-cell lymphoma-associated hemophagocytic lymphohistiocytosis: A case report.

Ademola S Ojo, Joseph Asemota, Somtochukwu Ojukwu, Ahmad Rajeh, Amina Bot, Caitlyn J Smith, Katsiaryna Laziuk, Mohammed Saleh

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Oncology letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Marginal Zone Lymphoma Manifesting as Macrophage Activation Syndrome: A Case Report.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ademola S OjoDepartment of Internal Medicine, Howard University Hospital, Washington, DC 20060, USA.
Joseph AsemotaDepartment of Internal Medicine, Howard University Hospital, Washington, DC 20060, USA.
Somtochukwu OjukwuDepartment of Internal Medicine, Howard University Hospital, Washington, DC 20060, USA.
Ahmad RajehDepartment of Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Amina BotDepartment of Internal Medicine, Howard University Hospital, Washington, DC 20060, USA.
Caitlyn J SmithDepartment of Pathology and Anatomical Sciences, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Katsiaryna LaziukDepartment of Pathology and Anatomical Sciences, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Mohammed SalehDepartment of Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Howard University Hospital · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition characterized by an exaggerated but dysregulated immune response resulting in hyperinflammation, with a potential for progression to multiple organ dysfunction and failure. Infectious diseases, inflammatory disorders, malignancies and immunodeficiency syndromes are known triggers of HLH in adults. The present study reported the case of a middle-aged man with HLH triggered by B-cell lymphoma who was successfully treated with dexamethasone; etoposide, prednisone, vincristine, cyclophosphamide, hydroxy-doxorubicin and rituximab chemotherapy; and multiple intrathecal methotrexate with a good outcome.

Indexed as

B-cell lymphomachemotherapyhemophagocytic histiocytosishyperinflammation

Identifiers

PMID35761945
PMCPMC9214690
OpenAlexW4281620817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.