Evidence map›Paper›PMID 35761802›Full record

ArticleExperimental and therapeutic medicine2022

COVID-19-associated acute appendicitis in adults. A report of five cases and a review of the literature.

Vasiliki Epameinondas Georgakopoulou, Aikaterini Gkoufa, Christos Damaskos, Petros Papalexis, Aikaterini Pierrakou, Sotiria Makrodimitri, Georgia Sypsa, Apostolos Apostolou, Stavroula Asimakopoulou, Serafeim Chlapoutakis and 3 more

Abstract readCase Reports
In one paragraph

Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  10. COVID-19 and liver injury in individuals with obesity.World journal of gastroenterology · 2023
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vasiliki Epameinondas GeorgakopoulouDepartment of Infectious Diseases, Laiko General Hospital, 11527 Athens, Greece.
Aikaterini GkoufaDepartment of Infectious Diseases, Laiko General Hospital, 11527 Athens, Greece.
Christos DamaskosRenal Transplantation Unit, Laiko General Hospital, 11527 Athens, Greece.
Petros PapalexisUnit of Endocrinology, First Department of Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Aikaterini PierrakouDepartment of Pathology, Sismanogleio Hospital, 15126 Athens, Greece.
Sotiria MakrodimitriDepartment of Infectious Diseases, Laiko General Hospital, 11527 Athens, Greece.
Georgia SypsaDepartment of Radiology, Laiko General Hospital, 11527 Athens, Greece.
Apostolos ApostolouDepartment of Infectious Diseases, Laiko General Hospital, 11527 Athens, Greece.
Stavroula AsimakopoulouDepartment of Infectious Diseases, Laiko General Hospital, 11527 Athens, Greece.
Serafeim ChlapoutakisDepartment of Thoracic Surgery, Agios Savvas Hospital, 11522 Athens, Greece.
Pagona SklapaniDepartment of Cytology, Mitera Hospital, 15123 Athens, Greece.
Nikolaos TrakasDepartment of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus has negatively affected patients and healthcare systems globally. Individuals with coronavirus disease 2019 (COVID-19) experience a wide range of respiratory symptoms, from mild flu-like symptoms to severe and potentially fatal pneumonia. Some patients report gastrointestinal symptoms, such as nausea, vomiting and abdominal pain in addition to the respiratory symptoms or as a separate presentation. Even though abdominal pain syndrome indicates acute appendicitis, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection should be considered as a possible diagnosis during this pandemic. However, there have been reports of a few cases of acute abdominal pain revealing acute appendicitis associated with SARS-CoV-2 infection. Appendectomy is challenging in COVID-19-infected patients with acute appendicitis as it includes high surgical risks for the patients, as well as hazards for healthcare professionals who are exposed to SARS-CoV-2. The present study reports five cases of adult patients with COVID-19 with simultaneous acute appendicitis. In addition, the present study aims to provide the framework for the diagnosis and management of adult patients with COVID-19 with acute appendicitis.

Indexed as

abdominal painacute abdomenacute appendicitisappendectomycoronavirus disease 2019

Identifiers

PMID35761802
PMCPMC9214594

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.