ArticleJBRA assisted reproduction2014
Changes of apoptosis regulation in the endometrium of infertile women with tubal factor and endometriosis undergoing in vitro fertilization treatment.
Article in JBRA assisted reproduction, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Endometriosis and the Hallmarks of Cancer.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Dysregulation of Key Biological Processes in Endometriosis Pathophysiology.Current molecular medicine · 2026Review
- Mechanism of Endometrial Receptivity Affected by Fibroids.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024Review
- Article
- The Pathological Role of miRNAs in Endometriosis.Biomedicines · 2023Review
- Candidate genes for infertility: an in-silico study based on cytogenetic analysis.BMC medical genomics · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo establish the relationship between the endometrial apoptosis parameters and endometrial receptivity in infertile women undergoing IVF treatment.
methods73 women with tubal infertility, 27 infertile women with endometriosis and 13 healthy fertile women (control group) were recruited into the study. 53 women with tubal factor of infertility and 17 patients with endometriosis later entered in the IVF protocol. Samples of endometrial tissue were used as the material for investigation. Endometrium was collected on the 20-24 days of non-conceptual cycle, using the Pipell suction curette. XIAP, PTEN and HSP27 mRNAs expression in the endometrial tissue was assessed by real time RT-PCR.
resultsIn women with tubal infertility the high level of XIAP, HSP27 and PTEN mRNAs expression in the endometrium was found. In infertile women with endometriosis the increase of XIAP and HSP27 mRNAs expression was noted. Success of the IVF outcome in women with tubal infertility was associated with maximal level of PTEN synthesis and in endometriosis group the pregnancy achievement after IVF treatment was noted in women with lower expression of XIAP mRNA.
conclusionThe high level of pro-apoptotic factors synthesis in the endometrium during window of implantation is associated with the readiness of endometrium to implantation.
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