Evidence map›Paper›PMID 35761311›Full record

ArticleParasites & vectors2022

Performance of Mini Parasep

Kulthida Y Kopolrat, Seri Singthong, Narong Khuntikeo, Watcharin Loilome, Chanika Worasith, Chutima Homwong, Chompunoot Wangboon, Patiwat Yasaka, Chatanun Eamudomkarn, Opal Pitaksakulrat and 5 more

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Diagnostic Performance of Mini ParasepMedicina (Kaunas, Lithuania) · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Partially purifiedMicrobiology spectrum · 2025
    Article
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  11. Article
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  14. Liver Flukes: Clonorchis and Opisthorchis.Advances in experimental medicine and biology · 2024
    Review
  15. Epidemiology and Geographical Distribution of Human Trematode Infections.Advances in experimental medicine and biology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Kulthida Y KopolratFaculty of Public Health, Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon, Thailand.ORCID http://orcid.org/0000-0001-6114-6554
Seri SingthongThe Office of Disease Prevention and Control 7 Khon Kaen, Department of Disease Control, Ministry of Public Health, Khon Kaen, Thailand.
Narong KhuntikeoCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Watcharin LoilomeCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Chanika WorasithCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Chutima HomwongCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Chompunoot WangboonSchool of Pre Clinic, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Patiwat YasakaFaculty of Management Technology, Rajamangala University of Technology Isan, Surin Campus, Surin, Thailand.
Chatanun EamudomkarnDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Opal PitaksakulratDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Krisnakorn TonkhamhakCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Arunee PaeyoCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Thomas CrellenInstitute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK.ORCID http://orcid.org/0000-0003-2934-1063
Jiraporn SithithawornFaculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Paiboon SithithawornCholangiocarcinoma Research Institute and Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. paib_sit@kku.ac.th.
Khon Kaen University · THMinistry of Public Health · THRajamangala University of Technology Isan · THSuranaree University of Technology · THUniversity of Oxford · GB

Funding

Wellcome TrustWellcome Trust 215919/Z/19/Z
6 · The paper itself

Abstract

backgroundControl and elimination of the liver fluke (Opisthorchis viverrini) is a primary preventive strategy against cholangiocarcinoma in Southeast Asia. A sensitive parasitological diagnostic method is required to facilitate a surveillance and control program. In this study, we evaluated the performance of Mini Parasep

methodsA cross-sectional survey for parasitic infection in residents aged > 15 years in a community in Kalasin province, Northeast Thailand, was conducted in 2018. Fecal samples were collected and screened by KK method, and a subset of samples was further examined by the stool kit and FECT methods. The results were analyzed for prevalence of parasitic infections in addition to the diagnostic performance of the methods for qualitative and quantitative detection of helminthiases.

resultsThe initial survey of parasitic infection determined by the KK method (n = 567) showed the prevalence of O. viverrini was 32.63%, followed by Taenia 2.65%, echinostomes 1.76%, hookworms 1.41%, Trichuris trichiura 0.53% and Strongyloides stercoralis 0.53%. Within a subset of samples tested with multiple diagnostics (n = 150), the detection rates of O. viverrini by the stool kit, FECT and KK methods were 27.3%, 30.7% and 28.7%, respectively. The diagnostic sensitivity for opisthorchiasis was similar for FECT (75.5%), KK(66.0%) and the stool kit (67.3%). For other parasitic infections, FECT and stool kit methods performed better than KK, particularly in detecting minute intestinal flukes (MIF), S. stercoralis and coinfections. When measuring the intensity of O. viverrini infection (fecal egg counts), the stool kit results showed a significant positive correlation with KK and FECT (P < 0.05).

conclusionsAs the stool kit is simple to use and shows a comparable performance to FECT, it may serve as an alternative method of fecal examination for screening of helminthiasis including opisthorchiasis.

Indexed as

HelminthiasisOpisthorchiasisOpisthorchisAcetatesAnimalsCross-Sectional StudiesFecesFormaldehydePrevalenceSensitivity and SpecificityThailandAcetatesethyl acetateFormaldehydeDiagnostic performanceFormalin-ethyl acetate concentration techniqueHelminthiasisKato-KatzMini Parasep® SF stool concentrator kitOpisthorchiasisOpisthorchis viverrini

Identifiers

PMID35761311
PMCPMC9235228
OpenAlexW4283593819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.