Evidence map›Paper›PMID 35761270›Full record

ArticleBMC public health2022

SARS-CoV-2 antibody prevalence among homeless people and shelter workers in Denmark: a nationwide cross-sectional study.

Alexandra R Röthlin Eriksen, Kamille Fogh, Rasmus B Hasselbalch, Henning Bundgaard, Susanne D Nielsen, Charlotte S Jørgensen, Bibi F S S Scharff, Christian Erikstrup, Susanne G Sækmose, Dorte K Holm and 25 more

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  9. [Health of homeless individuals during the COVID-19 pandemic].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Alexandra R Röthlin EriksenDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark. alexandra.rosengaard.roethlin.eriksen.01@regionh.dk.
Kamille FoghDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Rasmus B HasselbalchDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Henning BundgaardDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Susanne D NielsenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Charlotte S JørgensenStatens Serum Institut, Copenhagen, Denmark.
Bibi F S S ScharffDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Christian ErikstrupDepartment of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
Susanne G SækmoseDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Dorte K HolmDepartment of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Bitten AagaardDepartment of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
Jonas H KristensenDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Cecilie A BødkerDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Jakob B NorskDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Pernille B NielsenDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Lars ØstergaardDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Svend Ellermann-EriksenDepartment of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
Berit AndersenUniversity Research Clinic for Cancer Screening, Randers Regional Hospital, Randers, Denmark.
Henrik NielsenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Isik S JohansenDepartment of Research Medicine, University of Southern Denmark, Odense, Denmark.
Lothar WieseDepartment of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark.
Lone SimonsenDepartment of Science and Environment, University of Roskilde, Roskilde, Denmark.
Thea K FischerDepartment of Clinical Research, North Zealand Hospital, Hillerød, Denmark.
Fredrik FolkeDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Freddy LippertDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Sisse R OstrowskiDepartment of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Steen EthelbergStatens Serum Institut, Copenhagen, Denmark.
Anders KochStatens Serum Institut, Copenhagen, Denmark.
Anne-Marie VangstedStatens Serum Institut, Copenhagen, Denmark.
Tyra KrauseStatens Serum Institut, Copenhagen, Denmark.
Anders FomsgaardStatens Serum Institut, Copenhagen, Denmark.
Claus NielsenStatens Serum Institut, Copenhagen, Denmark.
Henrik UllumStatens Serum Institut, Copenhagen, Denmark.
Robert SkovStatens Serum Institut, Copenhagen, Denmark.
Kasper IversenDepartment of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople experiencing homelessness (PEH) and associated shelter workers may be at higher risk of infection with "Severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). The aim of this study was to determine the prevalence of SARS-CoV-2 among PEH and shelter workers in Denmark. DESIGN AND

methodsIn November 2020, we conducted a nationwide cross-sectional seroprevalence study among PEH and shelter workers at 21 recruitment sites in Denmark. The assessment included a point-of-care test for antibodies against SARS-CoV-2, followed by a questionnaire. The seroprevalence was compared to that of geographically matched blood donors considered as a proxy for the background population, tested using a total Ig ELISA assay.

resultsWe included 827 participants in the study, of whom 819 provided their SARS-CoV-2 antibody results. Of those, 628 were PEH (median age 50.8 (IQR 40.9-59.1) years, 35.5% female) and 191 were shelter workers (median age 46.6 (IQR 36.1-55.0) years and 74.5% female). The overall seroprevalence was 6.7% and was similar among PEH and shelter workers (6.8% vs 6.3%, p = 0.87); and 12.2% among all participants who engaged in sex work. The overall participant seroprevalence was significantly higher than that of the background population (2.9%, p < 0.001). When combining all participants who reported sex work or were recruited at designated safe havens, we found a significantly increased risk of seropositivity compared to other participants (OR 2.23, 95%CI 1.06-4.43, p = 0.02). Seropositive and seronegative participants reported a similar presence of at least one SARS-CoV-2 associated symptom (49% and 54%, respectively). INTERPRETATIONS: The prevalence of SARS-CoV-2 antibodies was more than twice as high among PEH and associated shelter workers, compared to the background population. These results could be taken into consideration when deciding in which phase PEH are eligible for a vaccine, as part of the Danish national SARS-CoV-2 vaccination program rollout.

fundingTrygFonden and HelseFonden.

Indexed as

COVID-19Ill-Housed PersonsAntibodies, ViralCOVID-19 VaccinesCross-Sectional StudiesDenmarkFemaleHealth PersonnelHumansMaleMiddle AgedPrevalenceSARS-CoV-2Seroepidemiologic StudiesAntibodies, ViralCOVID-19 Vaccines

Identifiers

PMID35761270
PMCPMC9238223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.