Evidence map›Paper›PMID 35761248›Full record

ArticleBMC women's health2022

Factors associated with uptake of contraceptives among HIV positive women on dolutegravir based anti-retroviral treatment-a cross sectional survey in urban Uganda.

Leah Mbabazi, Mariah Sarah Nabaggala, Suzanne Kiwanuka, Juliet Kiguli, Eva Laker, Arthur Kiconco, Stephen Okoboi, Mohammed Lamorde, Barbara Castelnuovo

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Modern Contraceptive Use Among Young Women in Kampala Slums: Research Findings from the TOPOWA Study.International journal of environmental research and public health · 2025
    Article
  5. Hidden risks of first-line regimen switching in antiretroviral therapy-treated patients.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Leah MbabaziInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda. leahmbabazi@gmail.com.
Mariah Sarah NabaggalaInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda.
Suzanne KiwanukaMakerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Juliet KiguliMakerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Eva LakerInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda.
Arthur KiconcoMakerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Stephen OkoboiInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda.
Mohammed LamordeInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda.
Barbara CastelnuovoInfectious Diseases Institute, P.O. Box 22418, Kampala, Uganda.
Infectious Diseases Institute · UGMakerere University · UG

Funding

HIV Co-infections in Uganda: TB, Cryptococcus, and Viral Hepatitis.D43TW009771 · FIC · JOHNS HOPKINS UNIVERSITY · PI CASTELNUOVO, BARBARA, KAMBUGU, ANDREW DDUNGU · 2014 to 2023
$3.3M
FIC NIH HHS D43 TW009771
6 · The paper itself

Abstract

backgroundIn May 2018, following the preliminary results of a study in Botswana that reported congenital anomalies in babies born to HIV-positive women taking dolutegravir drug, the WHO issued a teratogenicity alert. However, there are scarce data on the impact of this guidance on contraceptive uptake among women taking dolutegravir. We assessed the uptake of contraceptives in HIV-positive women of reproductive age on dolutegravir regimens.

methodsWe conducted a cross-sectional survey from April 2019 to July 2019 in five government health facilities in central Uganda, where dolutegravir-based regimens were offered as the preferred first-line antiretroviral treatment. We randomly selected 359 non-pregnant women aged 15-49 years taking dolutegravir-based regimens and interviewed them using semi-structured interviewer-administered questionnaires. We collected data on demographics, contraceptive use, individual, social, and health system factors. We described patients' characteristics using descriptive statistics and assessed factors associated with contraceptive uptake using a modified Poisson regression model.

resultsA total of 359 women were included in the study. The mean age was 37 years (standard deviation = 6.8) and overall contraceptive uptake was 38.4%. The most utilized method was injectable method at 58.4% followed by condoms (15%), intrauterine device (10.7%), pills (6.4%), implants (5.4%), and sterilization (0.7%). Predictors for contraceptive uptake were parity of 3-4 children (Adjusted Prevalence Ratio (APR) = 1.48, 95% confidence interval (CI): 1.14, 1.92) in reference to those with 1-2 children. There was reduced contraceptive uptake in women of the age range 40-49 years (APR = 0.45, CI: 0.21-0.94) compared to those aged 15-24 years. Unemployed women were less likely to use contraceptives (APR: 0.6, CI: 0.42- 0.94) than the formally employed. Contraceptive uptake was lower among women who did not discuss family planning with their partners (APR = 0.39, CI: 0.29-0.52) than those who discussed family planning with their partners and women who did not receive family planning counseling (APR = 0.56, CI: 0.34-0.92) than those who received family planning counselling.

conclusionWe observed a low-level uptake of contraceptives, with injectables as the most used method. Family planning counseling and partner discussion on family planning were associated with contraceptive uptake among the women who used dolutegravir-based regimens. There is a need for more strategies to integrate FP services and increase male involvement in HIV care programs.

Indexed as

Contraceptive AgentsHIV InfectionsAdultChildContraceptionContraception BehaviorCross-Sectional StudiesDolutegravirFamily Planning ServicesFemaleHeterocyclic Compounds, 3-RingHumansMaleMiddle AgedOxazinesPiperazinesContraceptive AgentsDolutegravirHeterocyclic Compounds, 3-RingOxazinesPiperazinesPyridonesAnti-retroviral treatmentContraceptives uptakeDolutegravir

Identifiers

PMID35761248
PMCPMC9238171
OpenAlexW4283711168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.