Evidence map›Paper›PMID 35761193›Full record

ArticleBMC nephrology2022

First-year mortality in incident dialysis patients: results of the Peridialysis study.

James Heaf, Maija Heiro, Aivars Petersons, Baiba Vernere, Johan V Povlsen, Anette Bagger Sørensen, Naomi Clyne, Inga Bumblyte, Alanta Zilinskiene, Else Randers and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Association between CKD-MBD and mortality in older patients with advanced CKD-results from the EQUAL study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 7 countries.

James HeafZealand University Hospital, Roskilde, Denmark. james.heaf@gmail.com.
Maija HeiroTurku University Hospital, Turku, Finland.
Aivars PetersonsP. Stradins University Hospital, Rīga, Latvia.
Baiba VernereP. Stradins University Hospital, Rīga, Latvia.
Johan V PovlsenAarhus University Hospital, Aarhus, Denmark.
Anette Bagger SørensenAarhus University Hospital, Aarhus, Denmark.
Naomi ClyneLund University and Skåne University Hospital, Lund, Sweden.
Inga BumblyteLithuanian University of Health Sciences, Kaunas, Lithuania.
Alanta ZilinskieneLithuanian University of Health Sciences, Kaunas, Lithuania.
Else RandersViborg Regional Hospital, Viborg, Denmark.
Niels LøkkegaardHolbaek Hospital, Holbæk, Denmark.
Mai RosenbergTartu University and University Hospital of Tartu, Tartu, Estonia.
Stig KjellevoldVestfold Hospital, Tønsberg, Norway.
Jan Dominik KampmannHospital of Southern Jutland, Soenderborg, Denmark.
Björn RoglandKristianstad Hospital, Kristianstad, Sweden.
Inger LagreidSt, Olav University Hospital, Trondheim, Norway.
Olof HeimburgerKarolinska Institutet, Stockholm, Sweden.
Abdul Rashid QureshiKarolinska Institutet, Stockholm, Sweden.
Bengt LindholmKarolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEAarhus University Hospital · DKLithuanian University of Health Sciences · LTPauls Stradiņš Clinical University Hospital · LVHolbæk Sygehus · DKKristianstad University · SERegionshospitalet Viborg · DKSkåne University Hospital · SESt Olav's University Hospital · NOSygehus Sønderjylland · DKSykehuset i Vestfold · NOTartu University Hospital · EETurku University Hospital · FIZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversy surrounds which factors are important for predicting early mortality after dialysis initiation (DI). We investigated associations of predialysis course and circumstances affecting planning and execution of DI with mortality following DI.

methodsAmong 1580 patients participating in the Peridialysis study, a study of causes and timing of DI, we registered features of predialysis course, clinical and biochemical data at DI, incidence of unplanned suboptimal DI, contraindications to peritoneal dialysis (PD) or hemodialysis (HD), and modality preference, actual choice, and cause of modality choice. Patients were followed for 12 months or until transplantation. A flexible parametric model was used to identify independent factors associated with all-cause mortality.

resultsFirst-year mortality was 19.33%. Independent factors predicting death were high age, comorbidity, clinical contraindications to PD or HD, suboptimal DI, high eGFR, low serum albumin, hyperphosphatemia, high C-reactive protein, signs of overhydration and cerebral symptoms at DI. Among 1061 (67.2%) patients who could select dialysis modality based on personal choice, 654 (61.6%) chose PD, 368 (34.7%) center HD and 39 (3.7%) home HD. The 12-months survival did not differ significantly between patients receiving PD and in-center HD.

conclusionsFirst-year mortality in incident dialysis patients was in addition to high age and comorbidity, associated with clinical contraindications to PD or HD, clinical symptoms, hyperphosphatemia, inflammation, and suboptimal DI. In patients with a "free" choice of dialysis modality based on their personal preferences, PD and in-center HD led to broadly similar short-term outcomes.

Indexed as

HyperphosphatemiaKidney Failure, ChronicPeritoneal DialysisHumansIncidenceRenal DialysisHemodialysisMortalityPeritoneal dialysisSurvival analysis

Identifiers

PMID35761193
PMCPMC9235232
OpenAlexW4283590438

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.