Evidence map›Paper›PMID 35761191›Full record

ArticleBMC pregnancy and childbirth2022

Outcomes of induction versus spontaneous onset of labour at 40 and 41 GW: findings from a prospective database, Sri Lanka.

Hemantha Senanayake, Ilaria Mariani, Emanuelle Pessa Valente, Monica Piccoli, Benedetta Armocida, Caterina Businelli, Mohamed Rishard, Benedetta Covi, Marzia Lazzerini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Hemantha SenanayakeUniversity Obstetrics Unit, De Soysa Hospital for Women, Colombo, Sri Lanka.
Ilaria MarianiInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo", WHO Collaborating Centre for Maternal and Child Health, Via dell'Istria 65/1, 34137, Trieste, Italy. ilaria.mariani@burlo.trieste.it.ORCID http://orcid.org/0000-0001-8260-4788
Emanuelle Pessa ValenteInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo", WHO Collaborating Centre for Maternal and Child Health, Via dell'Istria 65/1, 34137, Trieste, Italy.ORCID http://orcid.org/0000-0002-4741-4628
Monica PiccoliDepartment of Obstetrics & Gynaecology, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.
Benedetta ArmocidaDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging, National Institute of Health, Rome, Italy.
Caterina BusinelliDepartment of Obstetrics & Gynaecology, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.
Mohamed RishardUniversity Obstetrics Unit, De Soysa Hospital for Women, Colombo, Sri Lanka.
Benedetta CoviInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo", WHO Collaborating Centre for Maternal and Child Health, Via dell'Istria 65/1, 34137, Trieste, Italy.ORCID http://orcid.org/0000-0001-7635-0654
Marzia LazzeriniInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo", WHO Collaborating Centre for Maternal and Child Health, Via dell'Istria 65/1, 34137, Trieste, Italy.ORCID http://orcid.org/0000-0001-8608-2198
IRCCS Materno Infantile Burlo Garofolo · ITUniversity of Colombo · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe World Health Organization recommends induction of labour (IOL) for low risk pregnancy from 41 + 0 gestational weeks (GW). Nevertheless, in Sri Lanka IOL at 40 GW is a common practice. This study compares maternal/newborn outcomes after IOL at 40 GW (IOL40) or 41 GW (IOL41) versus spontaneous onset of labour (SOL).

methodsData were extracted from the routine prospective individual patient database of the Soysa Teaching Hospital for Women, Colombo. IOL and SOL groups were compared using logistic regression.

resultsOf 13,670 deliveries, 2359 (17.4%) were singleton and low risk at 40 or 41 GW. Of these, 456 (19.3%) women underwent IOL40, 318 (13.5%) IOL41, and 1585 (67.2%) SOL. Both IOL40 and IOL41 were associated with an increased risk of any maternal/newborn negative outcomes (OR = 2.21, 95%CI = 1.75-2.77, p < 0.001 and OR = 1.91, 95%CI = 1.47-2.48, p < 0.001 respectively), maternal complications (OR = 2.18, 95%CI = 1.71-2.77, p < 0.001 and OR = 2.34, 95%CI = 1.78-3.07, p < 0.001 respectively) and caesarean section (OR = 2.75, 95%CI = 2.07-3.65, p < 0.001 and OR = 3.01, 95%CI = 2.21-4.12, p < 0.001 respectively). Results did not change in secondary and sensitivity analyses.

conclusionsBoth IOL groups were associated with higher risk of negative outcomes compared to SOL. Findings, potentially explained by selection bias, local IOL protocols and CS practices, are valuable for Sri Lanka, particularly given contradictory findings from other settings.

Indexed as

Cesarean SectionLabor, InducedDatabases, FactualFemaleHumansInfant, NewbornMalePregnancySri LankaFull term pregnancyInduction of labourLate term pregnancyLow risk pregnanciesPregnancy outcomes

Identifiers

PMID35761191
PMCPMC9235207
OpenAlexW4283588744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.