ArticleMedizinische Klinik, Intensivmedizin und Notfallmedizin2023
[Patients requiring ICU treatment for acute poisoning-a 20-year single-center retrospective : Acute poisoning in intensive care].
Article in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- Association between prior ICU admission for drug overdose and ICU readmission: A retrospective registry-based study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- [GiftIQ: status quo of poisoning care in Germany : A nationwide survey assessing the current status in emergency and critical care medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Article
- Critical care management of the patient with pharmaceutical poisoning.Intensive care medicine · 2025Review
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Authors and funding
9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study presents a relevant collective of patients with acute poisoning admitted to a medical intensive care unit (ICU) of a tertiary care center in Germany during the past two decades.
objectivesOur study aims at providing an overview of patients' motivation for intoxication, their behavioral patterns, and subsequent treatment regimens. MATERIALS AND
methodsA total of 1030 patients admitted to the medical ICU of the RWTH Aachen University Hospital due to acute poisoning from January 1999 to December 2019 were included in our study. Demographic and clinical characteristics, as well as therapeutic procedures and outcomes were analyzed in detail and compared between age- and gender-related subgroups.
resultsThe most common substances that led to acute poisoning were medical substances, especially antidepressants. Substances varied between gender and age. The most frequent cause leading to acute poisoning in both females and males was suicidal intent associated with an intake of antidepressants. 286 patients (28%) developed ≥ 1 organ failure. The overall mortality was 2.6%. Comparing the first (1999-2009) and second decade (2010-2019), there was a distinct trend towards a more frequent intake of antidepressants and alcohol, whereas the use of benzodiazepines decreased.
conclusionsAlthough the overall patient mortality was low, patients with acute poisoning accounted for nearly 10% of all ICU admissions and required valuable resources despite limited capacity.
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