Evidence map›Paper›PMID 35760909›Full record

ArticleEuropean radiology2023

Regional shear wave elastography of Achilles tendinopathy in symptomatic versus contralateral Achilles tendons.

Scott K Crawford, Darryl Thelen, Janice M Yakey, Bryan C Heiderscheit, John J Wilson, Kenneth S Lee

Open access · greenAbstract read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Achilles Tendon Shear Wave Velocity Within a 1-Year Follow-Up After Non-Operatively Treated Rupture.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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  10. Observational
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  13. Achilles tendon and triceps surae muscle properties in athletes.European journal of applied physiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Scott K CrawfordDepartment of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA.ORCID http://orcid.org/0000-0003-3385-0813
Darryl ThelenDepartment of Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Janice M YakeyDepartment of Radiology, School of Medicine and Public Health, University of Wisconsin-Madison, E3/311, 600 Highland Ave, Madison, WI, 53792, USA.
Bryan C HeiderscheitDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA.
John J WilsonDepartment of Orthopedics & Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA.
Kenneth S LeeDepartment of Radiology, School of Medicine and Public Health, University of Wisconsin-Madison, E3/311, 600 Highland Ave, Madison, WI, 53792, USA. klee2@uwhealth.org.
University of Wisconsin–Madison · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
NCATS NIH HHS 1UL1RR025011NCATS NIH HHS 9U54TR000021NCATS NIH HHS UL1 TR002373NCRR NIH HHS UL1 RR025011Radiological Society of North America RSCH1317University of Wisconsin Madison Radiology Department Research and Development Fund #1204-001
6 · The paper itself

Abstract

objectivesUltrasound often corroborates clinical diagnosis of Achilles tendinopathy (AT). Traditional measures assess macromorphological features or use qualitative grading scales, primarily focused within the free tendon. Shear wave imaging can non-invasively quantify tendon elasticity, yet it is unknown if proximal structures are affected by tendon pathology. The purpose of the study was to determine the characteristics of both traditional sonographic measures and regional shear wave speed (SWS) between limbs in patients with AT.

methodsTwenty patients with chronic AT were recruited. Traditional sonographic measures of tendon structure were measured. Regional SWS was collected in a resting ankle position along the entire length of the tendon bilaterally. SWS measures were extracted and interpolated across evenly distributed points corresponding to the free tendon (FT), soleus aponeurosis (SA), and gastrocnemius aponeurosis (GA). Comparisons were made between limbs in both traditional sonographic measures and regional SWS.

resultsSymptomatic tendons were thicker (10.2 (1.9) vs. 6.8 (1.8) mm; p < 0.001) and had more hyperemia (p = 0.001) and hypoechogenicity (p = 0.002) than the contralateral tendon. Regional SWS in the FT was lower in the symptomatic limb compared to the contralateral limb (11.53 [10.99, 12.07] vs. 10.97 [10.43, 11.51]; p = 0.03). No differences between limbs were found for the SA (p = 0.13) or GA (p = 0.99).

conclusionsLower SWS was only observed in the FT in AT patients, indicating that alterations in tendon elasticity associated with AT were localized to the FT and did not involve the proximal passive tendon structures. KEY POINTS: • Baseline characteristics of a pilot sample of 20 subjects suffering from chronic Achilles tendinopathy showed differences in conventional sonographic measures of tendon thickness, qualitatively assessed hypoechogenicity, hyperemia, and quantitative measures of shear wave speed. • Regional shear wave speeds were lower in the free tendon but not in the proximal regions of the soleus or gastrocnemius aponeuroses in Achilles tendinopathy patients. • Using shear wave imaging to estimate tendon stiffness may prove beneficial for clinical validation studies to address important topics such as return to activity and the effectiveness of rehabilitation protocols.

Indexed as

Achilles TendonElasticity Imaging TechniquesHyperemiaTendinopathyElasticityHumansUltrasonographyAchilles tendonElasticityTendinopathyUltrasonography

Identifiers

PMID35760909
PMCPMC9771859
OpenAlexW4283640116

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.