Evidence map›Paper›PMID 35760877›Full record

ArticleMolecular psychiatry2022

Ventral prefrontal serotonin 1A receptor binding: a neural marker of vulnerability for mood disorder and suicidal behavior?

Spiro P Pantazatos, Nadine M Melhem, David A Brent, Francesca Zanderigo, Elizabeth A Bartlett, Mohammad Lesanpezeshki, Ainsley Burke, Jeffrey M Miller, J John Mann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Spiro P PantazatosMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA. spp2101@columbia.edu.ORCID http://orcid.org/0000-0002-9572-8816
Nadine M MelhemDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
David A BrentDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-5756-2157
Francesca ZanderigoMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA.ORCID http://orcid.org/0000-0001-6510-0676
Elizabeth A BartlettMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA.
Mohammad LesanpezeshkiMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA.
Ainsley BurkeMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA.
Jeffrey M MillerMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA.ORCID http://orcid.org/0000-0002-2206-9311
J John MannMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, NY, USA. jjm@columbia.edu.ORCID http://orcid.org/0000-0002-0265-6586
Columbia University Irving Medical Center · USUniversity of Pittsburgh · US

Funding

Suicidal Behavior: Aggression Subtypes, Childhood Adversity and Stress ResponseP50MH090964 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2013 to 2022
$23.6M
Research Training in Mood and Anxiety Disorders: From Animal Models to PatientsT32MH015144 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Eduardo David Leonardo · 1985 to 2026
$11.1M
Neurobiology of Depression and AntidepressantsR01MH040695 · NIMH · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI MANN, JOSEPH JOHN · 1986 to 2014
$7.1M
Familial Pathways to Early-OnSet Suicide AttemptsR01MH056390 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2002 to 2013
$4.5M
1/2 Inflammation and Stress Response in Familial and Nonfamilial Youth Suicidal BehaviorR01MH108039 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Nadine M. Melhem · 2015 to 2026
$3.2M
FAMILIAL PATHWAYS TO EARLY ONSET SUICIDE ATTEMPTSR10MH056390 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI MANN, JOSEPH J · 1997 to 2001
$1.1M
NIMH NIH HHS P50 MH090964NIMH NIH HHS R01 MH040695NIMH NIH HHS R01 MH056390NIMH NIH HHS R01 MH108039NIMH NIH HHS R10 MH056390NIMH NIH HHS T32 MH015144
6 · The paper itself

Abstract

Mood disorders and suicidal behavior have moderate heritability and are associated with altered corticolimbic serotonin 1A receptor (5-HT

Indexed as

Receptor, Serotonin, 5-HT1ASuicidal IdeationGenetic Predisposition to DiseaseHumansMood DisordersSerotoninReceptor, Serotonin, 5-HT1ASerotonin

Identifiers

PMID35760877
PMCPMC9722608
OpenAlexW4283706959

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.