ArticleNature microbiology2022
Three families of Asgard archaeal viruses identified in metagenome-assembled genomes.
Article in Nature microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 51 citations in OpenAlex.
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- Comprehensive analyses of archaeal viral genomes reveal genomic characteristics, divergence, and host interactions.Microbiome · 2026Article
- Diversity, ecology, cell biology and evolution of the Asgard archaea.Nature reviews. Microbiology · 2026Review
- The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Viromics approaches for the study of viral diversity and ecology in microbiomes.Nature reviews. Genetics · 2026Review
- Unraveling the diversity, function, and virus-host interactions of archaeal proviruses.ISME communications · 2026Article
- Advanced Strategies in Phage Research: Innovations, Applications, and Challenges.Microorganisms · 2025Review
- Metagenomic insights into taxonomic and functional patterns in shallow coastal and deep subseafloor sediments in the Western Pacific.Microbial genomics · 2025Article
- Expanding the Diversity ofViruses · 2025Article
- Comprehensive discovery and functional characterization of diverse prophages in the pig gut microbiome.Frontiers in microbiology · 2025Article
- Insights Into Phylogeny, Diversity and Functional Potential of Poseidoniales Viruses.Environmental microbiology · 2025Article
- Metagenomic characterization of viruses and mobile genetic elements associated with the DPANN archaeal superphylum.Nature microbiology · 2024Article
- A metagenomic catalogue of the ruminant gut archaeome.Nature communications · 2024Article
- Complete genomes of Asgard archaea reveal diverse integrated and mobile genetic elements.Genome research · 2024Article
- New Viruses Infecting Hyperthermophilic BacteriumViruses · 2024Article
- Methanotrophic Methanoperedens archaea host diverse and interacting extrachromosomal elements.Nature microbiology · 2024Article
- Article
- Identification of mobile genetic elements with geNomad.Nature biotechnology · 2024Article
- Megataxonomy and global ecology of the virosphere.The ISME journal · 2024Review
- Archaeal virus entry and egress.microLife · 2024Review
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7 authors at 5 institutions in 5 countries.
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Abstract
Asgardarchaeota harbour many eukaryotic signature proteins and are widely considered to represent the closest archaeal relatives of eukaryotes. Whether similarities between Asgard archaea and eukaryotes extend to their viromes remains unknown. Here we present 20 metagenome-assembled genomes of Asgardarchaeota from deep-sea sediments of the basin off the Shimokita Peninsula, Japan. By combining a CRISPR spacer search of metagenomic sequences with phylogenomic analysis, we identify three family-level groups of viruses associated with Asgard archaea. The first group, verdandiviruses, includes tailed viruses of the class Caudoviricetes (realm Duplodnaviria); the second, skuldviruses, consists of viruses with predicted icosahedral capsids of the realm Varidnaviria; and the third group, wyrdviruses, is related to spindle-shaped viruses previously identified in other archaea. More than 90% of the proteins encoded by these viruses of Asgard archaea show no sequence similarity to proteins encoded by other known viruses. Nevertheless, all three proposed families consist of viruses typical of prokaryotes, providing no indication of specific evolutionary relationships between viruses infecting Asgard archaea and eukaryotes. Verdandiviruses and skuldviruses are likely to be lytic, whereas wyrdviruses potentially establish chronic infection and are released without host cell lysis. All three groups of viruses are predicted to play important roles in controlling Asgard archaea populations in deep-sea ecosystems.
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