Evidence map›Paper›PMID 35760825›Full record

ArticleScientific reports2022

A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa.

Mohammad Reza Rahbar, Shaden M H Mubarak, Anahita Hessami, Bahman Khalesi, Navid Pourzardosht, Saeed Khalili, Kobra Ahmadi Zanoos, Abolfazl Jahangiri

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. EPY001, a Novel Monoclonal Antibody AgainstInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Applied and environmental microbiology · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Mohammad Reza RahbarPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shaden M H MubarakDepartment of Clinical Laboratory Science, Faculty of Pharmacy, University of Kufa, Najaf, Iraq.
Anahita HessamiSchool of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Bahman KhalesiDepartment of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization, Karaj, Iran.
Navid PourzardoshtBiochemistry Department, Guilan University of Medical Sciences, Rasht, Iran.
Saeed KhaliliDepartment of Biology Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran.
Kobra Ahmadi ZanoosYoung Researchers Club, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Abolfazl JahangiriApplied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Vanak Sq. Molasadra St., P.O. Box 1435915371, Tehran, Iran. fazel.jahangiri@yahoo.com.
Shiraz University of Medical Sciences · IRBaqiyatallah University of Medical Sciences · IRGuilan University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRRazi Vaccine and Serum Research Institute · IRShahid Rajaee Teacher Training University · IRUniversity of Kufa · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent outbreak of COVID-19 has increased hospital admissions, which could elevate the risk of nosocomial infections, such as A. baumannii and P. aeruginosa infections. Although effective vaccines have been developed against SARS-CoV-2, no approved treatment option is still available against antimicrobial-resistant strains of A. baumannii and P. aeruginosa. In the current study, an all-in-one antigen was designed based on an innovative, state-of-the-art strategy. In this regard, experimentally validated linear epitopes of spike protein (SARS-CoV-2), OmpA (A. baumannii), and OprF (P. aeruginosa) were selected to be harbored by mature OmpA as a scaffold. The selected epitopes were used to replace the loops and turns of the barrel domain in OmpA; OprF

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsCOVID-19EpitopesHumansPseudomonas aeruginosaSARS-CoV-2Spike Glycoprotein, CoronavirusEpitopesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID35760825
PMCPMC9237110
OpenAlexW4283713434

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.