Evidence map›Paper›PMID 35760543›Full record

ArticleBMJ open2022

Prevalence of breast fibroadenoma in healthy physical examination population in Guangdong province of China: a cross-sectional study.

Lijun Zhu, Xiaoqi Zeng, Shanshan Jiang, Simin Ruan, Huanrong Ma, Yingjia Li, Changsheng Ye, Jianyu Dong

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  5. Mammary Gland Microbiota in Benign Breast Diseases.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lijun ZhuDepartment of Medicine Ultrasonics, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Xiaoqi ZengBreast Center, Department of general surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Shanshan JiangInstitute of Hematological Research, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Simin RuanBreast Center, Department of general surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Huanrong MaDepartment of Medicine Ultrasonics, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Yingjia LiDepartment of Medicine Ultrasonics, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Changsheng YeBreast Center, Department of general surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China.
Jianyu DongBreast Center, Department of general surgery, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China dongjy@smu.edu.cn.ORCID 0000-0002-6005-6941
Nanfang Hospital · CNShaanxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide an accurate assessment of the prevalence of breast fibroadenoma in a large population and to confirm the diagnostic accuracy of ultrasound for fibroadenoma.

designThis was a cross-sectional survey.

settingThis research was conducted at Nanfang Hospital, Guangzhou, Guangdong, China.

participantsA total of 11 898 women aged 18-40 years who underwent breast screening between 1 January 2019 and 31 December 2019 were included in the fibroadenoma prevalence study. From 1 June 2019 to 31 December 2019, 342 breast lesions with pathology reports and preoperative ultrasound images were collected for diagnostic fibroadenoma testing (vs histological diagnostic testing). PRIMARY OUTCOME MEASURES: Pearson's χ

resultsOf the women aged 18-40 years, 27.6% (3285/11 898) had an ultrasound diagnosis offibroadenoma. Of these, the prevalence of fibroadenoma was stable across age groups (p=0.14) and did not differ between the left and right sides of the breast. Almost two-thirds of women presented with a single fibroadenoma, and most fibroadenomas did not exceed 1 cm in size. The sensitivity and specificity for fibroadenoma were 97.0% (95% CI for sensitivity: 93.7% to 98.8%) and 91.4% (95% CI for specificity: 85.4% to 95.5%) for ultrasonography, respectively.

conclusionsThe prevalence of fibroadenoma in South China is as high as 27.6%, and ultrasound could be used as a tool to diagnose fibroadenoma.

Indexed as

Breast NeoplasmsFibroadenomaBreastChinaCross-Sectional StudiesFemaleHumansPhysical ExaminationPrevalenceUltrasonography, Mammarybreast imagingepidemiologyultrasonography

Identifiers

PMID35760543
PMCPMC9237909
OpenAlexW4283585058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.