SynthesisPerfusion2023
Awake extracorporeal life support and physiotherapy in adult patients: A systematic review of the literature.
Synthesis in Perfusion, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Analgesia, sedation, and mobilization practices in pediatric patients supported with extracorporeal membrane oxygenation across Europe: an ESPNIC survey.European journal of pediatrics · 2026Article
- Early Cardiac Rehabilitation in Awake Veno-Arterial ECMO for Fulminant Myocarditis: A Case Report.Clinical case reports · 2026Article
- Long-term quality of life and functional outcomes in extracorporeal membrane oxygenation survivors.JHLT open · 2026Article
- Awake VV-ECMO for severe pneumonia caused by Elizabethkingia anophelis: a case report.BMC infectious diseases · 2026Article
- Extracorporeal life support for adult patients with ARDS.Intensive care medicine · 2025Review
- Early mobilization in patients on venoarterial extracorporeal membrane oxygenation: A scoping review.World journal of cardiology · 2025Article
- [Extracorporeal Life Support in Lung Transplantation and Beyond].Zentralblatt fur Chirurgie · 2025Review
- Extracorporeal membrane oxygenation for prevention of barotrauma in patients with respiratory failure: A scoping review.Artificial organs · 2025Article
- Lessons Learned From Awake ECMO Approach in Covid-19-Related Acute Respiratory Distress Syndrome - a Scoping Review.Therapeutics and clinical risk management · 2025Review
- Feasibility and safety of upper limb extremity ergometer exercise in the cardiac intensive care unit in critically ill patients with cardiac disease: a prospective observational study.Frontiers in physiology · 2025Article
- Prevalence and Neurological Outcomes of Comatose Patients With Extracorporeal Membrane Oxygenation.Journal of cardiothoracic and vascular anesthesia · 2024Observational
- The ProtekDuo Cannula: A Comprehensive Review of Efficacy and Clinical Applications in Right Ventricular Failure.Journal of clinical medicine · 2024Review
- ECMO-TO-GO: Application of a portable on the body veno-arterial ECMO device in a bridge-to-transplantation setting.JHLT open · 2024Article
- Severe Lung Dysfunction and Pulmonary Blood Flow during Extracorporeal Membrane Oxygenation.Journal of clinical medicine · 2024Article
- Extracorporeal Membrane Oxygenation.Respiratory care · 2023Review
- [Active mobilization during extracorporeal membrane oxygenation-safety first].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe Awake Extracorporeal Life Support (ECLS) practice combined with physiotherapy is increasing. However, available evidence for this approach is limited, with unclear indications on timing, management, and protocols. This review summarizes available literature regarding Awake ECLS and physiotherapy application rates, practices, and outcomes in adults, providing indications for future investigations.
methodsFour databases were screened from inception to February 2021, for studies reporting adult Awake ECLS with/without physiotherapy. Primary outcome was hospital discharge survival, followed by Extracorporeal Membrane Oxygenation (ECMO) duration, extubation, Intensive Care Unit stay.
resultsTwenty-nine observational studies and one randomized study were selected, including 1,157 patients (males
conclusionAwake ECLS strategy associated with physiotherapy is performed regardless of cannulation approach. Ambulation, as main objective, is achieved in almost half the population examined. Prospective studies are needed to evaluate safety and efficacy of physiotherapy during Awake ECLS, and suitable patient selection. Guidelines are required to identify appropriate assessment/evaluation tools for Awake ECLS patients monitoring.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.