Evidence map›Paper›PMID 35760499›Full record

ArticleBMJ case reports2022

Metastatic insidious super giant basal cell carcinoma.

Maryam Ahmed, Tinatin Muradashvili, Sara Soliman, Medhat Ghaly

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. A super-giant basal cell carcinoma of the scalp.Oxford medical case reports · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maryam AhmedYale-Waterbury Internal Medicine Residency, Yale University School of Medicine, Waterbury, Connecticut, USA.
Tinatin MuradashviliYale-Waterbury Internal Medicine Residency, Yale University School of Medicine, Waterbury, Connecticut, USA.
Sara SolimanYale-Waterbury Internal Medicine Residency, Yale University School of Medicine, Waterbury, Connecticut, USA.
Medhat GhalyYale-Waterbury Internal Medicine Residency, Yale University School of Medicine, Waterbury, Connecticut, USA medhat.abdelmessih@yale.edu.ORCID http://orcid.org/0000-0001-9814-5993
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A middle-aged woman presented with a mechanical fall. Physical examination revealed a massive purulent ulcerated lesion spanning her entire back and axilla, which had reportedly been brewing for over a decade. Punch biopsy revealed infiltrative basal cell carcinoma. She was treated with Vismodegib, with a remarkable decrease in the size of the cancer. However, surveillance imaging after 6 months of treatment revealed new bone metastases. In the setting of progressive disease, medical therapy was switched to cemiplimab instead. Basal cell carcinoma is commonly known as a benign tumour of the skin, rarely larger than 5 cm. Here, we discuss the entity of metastatic super giant basal cell carcinoma; this case is one of the largest reported lesions. As locoregional therapy, such as surgery is sometimes not appropriate for such advanced lesions, we discuss the current forefront of therapy including oral hedgehog pathway and check point inhibitors.

Indexed as

Basal Cell CarcinomaSkin NeoplasmsBiopsyFemaleHedgehog ProteinsHumansMiddle AgedSkinHedgehog ProteinsCancer interventionDepressive disorderImmunologySkin cancerSurgical oncology

Identifiers

PMID35760499
PMCPMC9237944
OpenAlexW4283591321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.