Evidence map›Paper›PMID 35760338›Full record

ArticleContemporary clinical trials2022

Contingency management and cognitive behavior therapy for smoking cessation among veterans with posttraumatic stress disorder: Design and methodology of a randomized clinical trial.

Stephanie Y Wells, Stefanie T LoSavio, Tapan A Patel, Mariah K Evans, Jean C Beckham, Patrick Calhoun, Eric A Dedert

Open access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Stephanie Y WellsDurham VA Healthcare System, Durham, NC, USA; VISN 6 Mid-Atlantic MIRECC, Durham, NC, USA.
Stefanie T LoSavioDurham VA Healthcare System, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Tapan A PatelDurham VA Healthcare System, Durham, NC, USA.
Mariah K EvansDurham VA Healthcare System, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Jean C BeckhamDurham VA Healthcare System, Durham, NC, USA; VISN 6 Mid-Atlantic MIRECC, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Patrick CalhounDurham VA Healthcare System, Durham, NC, USA; VISN 6 Mid-Atlantic MIRECC, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
Eric A DedertDurham VA Healthcare System, Durham, NC, USA; VISN 6 Mid-Atlantic MIRECC, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Department of Veterans Affairs Office of Mental Health and Suicide Prevention, Washington, DC, USA. Electronic address: Eric.Dedert@va.gov.
Durham VA Health Care System · USDuke University · USMental Illness Research, Education and Clinical Centers · USVA Mid-Atlantic Health Care Network · US

Funding

CPT-SMART for Treatment of PTSD and Cigarette SmokingI01CX001757 · VA · DURHAM VA MEDICAL CENTER · PI Eric A Dedert · 2020 to 2026
–
CSRD VA I01 CX001757
6 · The paper itself

Abstract

backgroundSmoking is a prevalent concern among Veterans, especially those with posttraumatic stress disorder (PTSD). Despite the availability of interventions for smoking cessation, these treatments have not been as effective among Veteran populations, particularly Veterans with PTSD. The present study seeks to describe the methods of a randomized clinical trial examining the efficacy of CPT-SMART, a multidimensional treatment combining cognitive processing therapy (CPT) for PTSD, smoking cessation counseling, pharmacotherapy, and contingency management (CM) compared to a yoked comparison group.

methodsOne hundred twenty Veterans with PTSD who smoke cigarettes will be enrolled. All participants will receive CPT in addition to counseling and pharmacotherapy for smoking cessation. Participants will be randomized to the CPT-SMART condition, which includes monetary reinforcement that is contingent on bioverification of smoking abstinence (i.e., contingency management), or a yoked comparison with monetary reinforcement matched to the participant to whom they are yoked. The primary outcome is bioverified smoking abstinence at the 6-month follow-up appointment.

conclusionIf shown efficacious, a combined PTSD and smoking treatment plus incentive-based approach for smoking could be implemented into specialty PTSD programs. The positive public health impact of reducing smoking among Veterans with PTSD could be enormous as it would prevent significant smoking-related morbidity and mortality.

Indexed as

Cognitive Behavioral TherapySmoking CessationStress Disorders, Post-TraumaticVeteransHumansRandomized Controlled Trials as TopicTobacco Use Cessation DevicesTreatment OutcomeCognitive processing therapyContingency managementPTSDSmokingSmoking cessation

Identifiers

PMID35760338
PMCPMC9420819
OpenAlexW4283516185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.