Evidence map›Paper›PMID 35760254›Full record

ArticleBioorganic & medicinal chemistry letters2022

Discovery of 2-thiobenzimidazoles as noncovalent inhibitors of SARS-CoV-2 main protease.

Davide Deodato, Nadeem Asad, Timothy M Dore

Abstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Davide DeodatoNew York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
Nadeem AsadNew York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
Timothy M DoreNew York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates; Department of Chemistry, University of Georgia, Athens, GA 30602, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of antiviral agents against SARS-CoV-2 is an important step toward ending the COVID-19 pandemic and to tackle future outbreaks. In this context, the main protease (M

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2Antiviral AgentsBenzimidazolesCoronavirus 3C ProteasesCysteine EndopeptidasesHumansMolecular Docking SimulationPandemicsProtease InhibitorsViral Nonstructural Proteins3C-like proteinase, SARS-CoV-2Antiviral AgentsBenzimidazolesCoronavirus 3C ProteasesCysteine EndopeptidasesProtease InhibitorsViral Nonstructural Proteins

Identifiers

PMID35760254
PMCPMC9225965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.